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Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Tacrolimus in Kidney Transplantation

BACKGROUND: Tacrolimus (Tac, or FK506), a calcineurin inhibitor (CNI), is the first-line immu-nosuppressant which consists of the footstone as immunosuppressive regimens in kidney transplantation. However, the drug toxicity and the significant differences of pharmacokinetics (PK) and pharmacodynam-i...

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Detalles Bibliográficos
Autores principales:	Yu, Meng, Liu, Mouze, Zhang, Wei, Ming, Yingzi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182932/ https://www.ncbi.nlm.nih.gov/pubmed/29380698 http://dx.doi.org/10.2174/1389200219666180129151948

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