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Molecular mechanism of panaxydol on promoting axonal growth in PC12 cells

Nerve growth factor (NGF) promotes axonal growth in PC12 cells primarily by regulating the RTK-RAS-MEK-ERK pathway. Panaxydol, a polyacetylene isolated from Panax notoginseng, can mimic the effects of NGF. Panaxydol promotes neurite outgrowth in PC12 cells, but its molecular mechanism remains unclea...

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Detalles Bibliográficos
Autores principales:	Li, Wei-Peng, Ma, Ke, Jiang, Xiao-Yan, Yang, Rui, Lu, Pei-Hua, Nie, Bao-Ming, Lu, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183029/ https://www.ncbi.nlm.nih.gov/pubmed/30233066 http://dx.doi.org/10.4103/1673-5374.239439

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