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OMV-based vaccine formulations against Shiga toxin producing Escherichia coli strains are both protective in mice and immunogenic in calves

Strains of Shiga toxin-producing Escherichia coli (STEC) can cause the severe Hemolytic Uremic Syndrome (HUS). Shiga toxins are protein toxins that bind and kill microvascular cells, damaging vital organs. No specific therapeutics or vaccines have been licensed for use in humans yet. The most common...

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Detalles Bibliográficos
Autores principales: Fingermann, Matias, Avila, Lucía, De Marco, Maria Belén, Vázquez, Luciana, Di Biase, Darío Nicolás, Müller, Andrea Verónica, Lescano, Mirta, Dokmetjian, José Christian, Fernández Castillo, Sonsire, Pérez Quiñoy, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183318/
https://www.ncbi.nlm.nih.gov/pubmed/29923791
http://dx.doi.org/10.1080/21645515.2018.1490381

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