Genetic and epigenetic analyses guided by high resolution whole-genome SNP array reveals a possible role of CHEK2 in Wilms tumour susceptibility

Wilms tumour (WT), the most frequent malignant childhood renal tumour, shows a high degree of genetic and epigenetic heterogeneity. Loss of imprinting on chromosome 11p15 is found in a large fraction of cases and mutations in a few genes, including WT1, CTNNB1, WTX, TP53 and, more recently, SIX1, SI...

Descripción completa

Detalles Bibliográficos
Autores principales: Ciceri, Sara, Gamba, Beatrice, Corbetta, Paola, Mondini, Patrizia, Terenziani, Monica, Catania, Serena, Nantron, Marilina, Bianchi, Maurizio, D’Angelo, Paolo, Torri, Federica, Macciardi, Fabio, Collini, Paola, Di Martino, Martina, Melchionda, Fraia, Di Cataldo, Andrea, Spreafico, Filippo, Radice, Paolo, Perotti, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183341/
https://www.ncbi.nlm.nih.gov/pubmed/30344923
http://dx.doi.org/10.18632/oncotarget.26123

Ejemplares similares

Ejemplares similares