Cargando…

Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes

Pediatric glioblastoma (GBM) is a relatively rare brain tumor in children that has a dismal prognosis. Surgery followed by radiotherapy is the main treatment protocol used for older patients. The benefit of adjuvant chemotherapy is still limited due to a poor understanding of the underlying molecula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alhajala, Hisham S., Nguyen, Ha S., Shabani, Saman, Best, Benjamin, Kaushal, Mayank, Al-Gizawiy, Mona M., Erin Ahn, Eun-Young, Knipstein, Jeffery A., Mirza, Shama, Schmainda, Kathleen M., Chitambar, Christopher R., Doan, Ninh B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183347/ https://www.ncbi.nlm.nih.gov/pubmed/30344926 http://dx.doi.org/10.18632/oncotarget.26137

Ejemplares similares

Identification of radiation responsive genes and transcriptome profiling via complete RNA sequencing in a stable radioresistant U87 glioblastoma model
por: Doan, Ninh B., et al.
Publicado: (2018)

Acid ceramidase confers radioresistance to glioblastoma cells
por: Doan, Ninh B., et al.
Publicado: (2017)

Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency
por: Doan, Ninh B., et al.
Publicado: (2017)

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1
por: Alhajala, Hisham S., et al.
Publicado: (2020)

Glioblastoma in the setting of prior lower grade gliomas – insights from SEER database
por: Nguyen, Ha Son, et al.
Publicado: (2018)

HGG-06. CHARACTERIZATION OF THE EFFECT OF THE ORAL IRON-MIMETIC GALLIUM MALTOLATE ON PEDIATRIC GLIOBLASTOMA GROWTH IN VIVO
por: Al-Gizawiy, Mona M, et al.
Publicado: (2023)

TIPS-03 A PHASE 1 STUDY OF GALLIUM MALTOLATE (GAM) IN PATIENTS WITH RECURRENT GLIOBLASTOMA (GBM)
por: Connelly, Jennifer, et al.
Publicado: (2023)

Molecular Markers of Therapy-Resistant Glioblastoma and Potential Strategy to Combat Resistance
por: Nguyen, Ha S., et al.
Publicado: (2018)

ATRT-03. THE ORAL IRON-MIMETIC GALLIUM MALTOLATE INHIBITS ATRT IN VIVO – IMAGING AND HISTOLOGICAL CHARACTERIZATION
por: Al-Gizawiy, Mona, et al.
Publicado: (2023)

Acid ceramidase is a novel drug target for pediatric brain tumors
por: Doan, Ninh B., et al.
Publicado: (2017)

Basal Ganglia Iron Content Increases with Glioma Severity Using Quantitative Susceptibility Mapping: A Potential Biomarker of Tumor Severity
por: Reith, Thomas P., et al.
Publicado: (2022)

Molecular Targeting of Acid Ceramidase in Glioblastoma: A Review of Its Role, Potential Treatment, and Challenges
por: Nguyen, Ha S., et al.
Publicado: (2018)

Methotrexate-induced Leukoencephalopathy without Typical Restricted Diffusion on Diffusion-weighted Imaging and the Utility of Magnetic Resonance Spectroscopy to Support the Diagnosis
por: Doan, Ninh, et al.
Publicado: (2018)

Intracranial hemangioblastoma – A SEER-based analysis 2004–2013
por: Nguyen, Ha Son, et al.
Publicado: (2018)

Coincidence of an anterior cerebral artery aneurysm and a glioblastoma: case report and review of literature
por: Nguyen, Ha Son, et al.
Publicado: (2015)

CD44‐associated radioresistance of glioblastoma in irradiated brain areas with optimal tumor coverage
por: Liu, Wei‐Hsiu, et al.
Publicado: (2019)

Radioresistance in Glioblastoma and the Development of Radiosensitizers
por: Ali, Md Yousuf, et al.
Publicado: (2020)

Dilemmas surrounding the diagnosis of deep brain stimulation electrode infection without associated wound complications: A series of two cases
por: Nguyen, Ha Son, et al.
Publicado: (2016)

Co-presentation of a subdural empyema and an infected ventriculoperitoneal shunt in an adult patient: A rare complication with review of literature
por: Nguyen, Ha Son, et al.
Publicado: (2015)

Pure tentorial subdural hematoma from rupture of aneurysm along the transmastoid branches of the occipital artery
por: Nguyen, Ha Son, et al.
Publicado: (2016)

A molecular view of the radioresistance of gliomas
por: Han, Xuetao, et al.
Publicado: (2017)

Non-enhancing Glioblastoma: A Case Report
por: Park, Dahye, et al.
Publicado: (2023)

Good Outcomes with the Intraventricular Vancomycin Therapy in a Patient with Ruptured Brain Abscesses
por: Doan, Ninh, et al.
Publicado: (2018)

The Role of Magnetic Resonance Imaging and Computed Tomography in Spinal Cord Injury
por: Hussain, Omar, et al.
Publicado: (2023)

Marsupialization and distal obliteration of a lumbosacral dural ectasia in a nonsyndromic, adult patient
por: Nguyen, Ha Son, et al.
Publicado: (2015)

Traumatic spondyloptosis at the cervico-thoracic junction without neurological deficits
por: Nguyen, Ha Son, et al.
Publicado: (2016)

Good outcomes in a patient with a Duret hemorrhage from an acute subdural hematoma
por: Nguyen, Ha Son, et al.
Publicado: (2016)

TRPM8 is required for survival and radioresistance of glioblastoma cells
por: Klumpp, Dominik, et al.
Publicado: (2017)

Cathepsins Trigger Cell Death and Regulate Radioresistance in Glioblastoma
por: Ding, Xiaofeng, et al.
Publicado: (2022)

Hedgehog signaling and the glioma-associated oncogene in cancer radioresistance
por: Zhang, Li, et al.
Publicado: (2023)

Granulomatous amebic encephalitis following hematopoietic stem cell transplantation
por: Doan, Ninh, et al.
Publicado: (2015)

Safe Use of Tissue Plasminogen Activator in Conjunction with the Integra Camino Bolt for the Drainage of Chronic Subdural Hematoma
por: Doan, Ninh B., et al.
Publicado: (2018)

The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance
por: Torrisi, Filippo, et al.
Publicado: (2020)

Purine metabolism promotes radioresistance and is a therapeutic target in glioblastoma
por: Zhou, Weihua, et al.
Publicado: (2020)

Bioinformatics analysis of microenvironment-related genes associated with radioresistance in glioblastoma
por: Liu, Yun, et al.
Publicado: (2020)

A Rare Extra-Axial Midline Tentorial Adult Medulloblastoma with Dural-Tail Sign Mimicking a Meningioma
por: Doan, Ninh Ba, et al.
Publicado: (2018)

Radiation-induced bystander effect in non-irradiated glioblastoma spheroid cells
por: Faqihi, Fahime, et al.
Publicado: (2015)

Expression of TIP-1 Confers Radioresistance of Malignant Glioma Cells
por: Han, Miaojun, et al.
Publicado: (2012)

Difference in Acquired Radioresistance Induction Between Repeated Photon and Particle Irradiation
por: Sato, Katsutoshi, et al.
Publicado: (2019)

IMG-10. MAGNETIC RESONANCE FUNCTIONAL IMAGING BIOMARKER FOR DISTINGUISHING HIGH GRADE FROM LOW GRADE PEDIATRIC BRAIN TUMORS
por: Kelly, Teresa Gross, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ca2mapd1qqovk1i997c1ip6ieg