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Effects of a single long-acting muscarinic antagonist agent and a long-acting muscarinic antagonist/long-acting β2-adrenoceptor agonist combination on lung function and symptoms in untreated COPD patients in Japan

BACKGROUND: A large body of evidence suggests that long-acting β2-adrenoceptor agonist (LABA)/long-acting muscarinic antagonist (LAMA) combinations induce a strong synergistic bronchodilatory effect in human isolated airways. Moreover, a recent post hoc analysis demonstrated clinical synergism betwe...

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Detalles Bibliográficos
Autores principales:	Yamada, Hideyasu, Hida, Norihito, Hizawa, Nobuyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183692/ https://www.ncbi.nlm.nih.gov/pubmed/30349222 http://dx.doi.org/10.2147/COPD.S179285

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