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PANDA-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data

SUMMARY: Compared with the numerous software tools developed for identification and quantification of -omics data, there remains a lack of suitable tools for both downstream analysis and data visualization. To help researchers better understand the biological meanings in their -omics data, we presen...

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Detalles Bibliográficos
Autores principales: Chang, Cheng, Xu, Kaikun, Guo, Chaoping, Wang, Jinxia, Yan, Qi, Zhang, Jian, He, Fuchu, Zhu, Yunping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6184437/
https://www.ncbi.nlm.nih.gov/pubmed/29790911
http://dx.doi.org/10.1093/bioinformatics/bty408
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author Chang, Cheng
Xu, Kaikun
Guo, Chaoping
Wang, Jinxia
Yan, Qi
Zhang, Jian
He, Fuchu
Zhu, Yunping
author_facet Chang, Cheng
Xu, Kaikun
Guo, Chaoping
Wang, Jinxia
Yan, Qi
Zhang, Jian
He, Fuchu
Zhu, Yunping
author_sort Chang, Cheng
collection PubMed
description SUMMARY: Compared with the numerous software tools developed for identification and quantification of -omics data, there remains a lack of suitable tools for both downstream analysis and data visualization. To help researchers better understand the biological meanings in their -omics data, we present an easy-to-use tool, named PANDA-view, for both statistical analysis and visualization of quantitative proteomics data and other -omics data. PANDA-view contains various kinds of analysis methods such as normalization, missing value imputation, statistical tests, clustering and principal component analysis, as well as the most commonly-used data visualization methods including an interactive volcano plot. Additionally, it provides user-friendly interfaces for protein-peptide-spectrum representation of the quantitative proteomics data. AVAILABILITY AND IMPLEMENTATION: PANDA-view is freely available at https://sourceforge.net/projects/panda-view/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-61844372018-10-18 PANDA-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data Chang, Cheng Xu, Kaikun Guo, Chaoping Wang, Jinxia Yan, Qi Zhang, Jian He, Fuchu Zhu, Yunping Bioinformatics Applications Notes SUMMARY: Compared with the numerous software tools developed for identification and quantification of -omics data, there remains a lack of suitable tools for both downstream analysis and data visualization. To help researchers better understand the biological meanings in their -omics data, we present an easy-to-use tool, named PANDA-view, for both statistical analysis and visualization of quantitative proteomics data and other -omics data. PANDA-view contains various kinds of analysis methods such as normalization, missing value imputation, statistical tests, clustering and principal component analysis, as well as the most commonly-used data visualization methods including an interactive volcano plot. Additionally, it provides user-friendly interfaces for protein-peptide-spectrum representation of the quantitative proteomics data. AVAILABILITY AND IMPLEMENTATION: PANDA-view is freely available at https://sourceforge.net/projects/panda-view/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2018-10-15 2018-05-22 /pmc/articles/PMC6184437/ /pubmed/29790911 http://dx.doi.org/10.1093/bioinformatics/bty408 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Chang, Cheng
Xu, Kaikun
Guo, Chaoping
Wang, Jinxia
Yan, Qi
Zhang, Jian
He, Fuchu
Zhu, Yunping
PANDA-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data
title PANDA-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data
title_full PANDA-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data
title_fullStr PANDA-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data
title_full_unstemmed PANDA-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data
title_short PANDA-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data
title_sort panda-view: an easy-to-use tool for statistical analysis and visualization of quantitative proteomics data
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6184437/
https://www.ncbi.nlm.nih.gov/pubmed/29790911
http://dx.doi.org/10.1093/bioinformatics/bty408
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