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POH1 deubiquitinates pro-interleukin-1β and restricts inflammasome activity
Inflammasome activation is essential for host defence against invading pathogens, but is also involved in various forms of inflammatory diseases. The processes that control inflammasome activity are thus important for averting excessive immune responses and tissue damage. Here we show that the deubi...
Autores principales: | Zhang, Li, Liu, Yun, Wang, Boshi, Xu, Guiqin, Yang, Zhaojuan, Tang, Ming, Ma, Aihui, Jing, Tiantian, Xu, Xiaoli, Zhang, Xiaoren, Liu, Yongzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185913/ https://www.ncbi.nlm.nih.gov/pubmed/30315153 http://dx.doi.org/10.1038/s41467-018-06455-z |
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