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MicroRNA binding mediated Functional sequence variant in 3′-UTR of DNA repair Gene XPC in Age-related Cataract

DNA oxidative damage repair is strongly involved in the pathogenesis of age-related cataract (ARC). The sequence variants of in coding region of DNA repair genes have been shown to be associated with ARC. It is known that single nucleotide polymorphisms (SNPs) in the 3′-terminal untranslated region...

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Detalles Bibliográficos
Autores principales: Zou, Xi, Kang, Lihua, Yang, Mei, Wu, Jian, Guan, Huaijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185952/
https://www.ncbi.nlm.nih.gov/pubmed/30315181
http://dx.doi.org/10.1038/s41598-018-33071-0

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