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Myogenin promotes myocyte fusion to balance fibre number and size
Each skeletal muscle acquires its unique size before birth, when terminally differentiating myocytes fuse to form a defined number of multinucleated myofibres. Although mice in which the transcription factor Myogenin is mutated lack most myogenesis and die perinatally, a specific cell biological rol...
Autores principales: | Ganassi, Massimo, Badodi, Sara, Ortuste Quiroga, Huascar Pedro, Zammit, Peter S., Hinits, Yaniv, Hughes, Simon M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185967/ https://www.ncbi.nlm.nih.gov/pubmed/30315160 http://dx.doi.org/10.1038/s41467-018-06583-6 |
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