Cargando…
MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway
Emerging evidence has shown that microRNA-126 (miR-126) is aberrantly downregulated and plays a vital role in carcinogenesis in various cancers, including HCC. However, the underlying biological mechanisms of miR-126 in HCC are still largely unknown. In present study, we found that miR-126 was downr...
Autores principales: | Bao, Jie, Yu, Yan, Chen, Jianan, He, Yuting, Chen, Xiaolong, Ren, Zhigang, Xue, Chen, Liu, Liwen, Hu, Qiuyue, Li, Juan, Cui, Guangying, Sun, Ranran |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185973/ https://www.ncbi.nlm.nih.gov/pubmed/30315225 http://dx.doi.org/10.1038/s41419-018-1020-0 |
Ejemplares similares
-
Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer
por: Chen, Jianan, et al.
Publicado: (2019) -
Downregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer
por: Xue, Chen, et al.
Publicado: (2018) -
Association of genetic variants in ATR-CHEK1 and ATM-CHEK2 pathway genes with risk of colorectal cancer in a Chinese population
por: Wang, Shijia, et al.
Publicado: (2018) -
CD44 is overexpressed and correlated with tumor progression in gallbladder cancer
por: He, Yuting, et al.
Publicado: (2018) -
Associations of ATR and CHEK1 Single Nucleotide Polymorphisms with Breast Cancer
por: Lin, Wei-Yu, et al.
Publicado: (2013)