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Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factors

Sorafenib, a multikinase inhibitor with antiproliferative, antiangiogenic, and proapoptotic properties, constitutes the only effective first-line drug approved for the treatment of advanced hepatocellular carcinoma (HCC). Despite its capacity to increase survival in HCC patients, its success is quit...

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Detalles Bibliográficos
Autores principales:	Méndez-Blanco, Carolina, Fondevila, Flavia, García-Palomo, Andrés, González-Gallego, Javier, Mauriz, José L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185986/ https://www.ncbi.nlm.nih.gov/pubmed/30315182 http://dx.doi.org/10.1038/s12276-018-0159-1

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