p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification

BACKGROUND: Malignant pleural mesothelioma (MPM) is an orphan disease that is difficult to treat using traditional chemotherapy, an approach which has been effective in other types of cancer. Most chemotherapeutics cause DNA damage leading to cell death. Recent discoveries have highlighted a potenti...

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Detalles Bibliográficos
Autores principales: Tian, Kun, Bakker, Emyr, Hussain, Michelle, Guazzelli, Alice, Alhebshi, Hasen, Meysami, Parisa, Demonacos, Constantinos, Schwartz, Jean-Marc, Mutti, Luciano, Krstic-Demonacos, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186085/
https://www.ncbi.nlm.nih.gov/pubmed/30316293
http://dx.doi.org/10.1186/s12967-018-1650-0

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