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Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology

BACKGROUND: Despite diverging levels of amyloid-β (Aβ) and TAU pathology, different mouse models, as well as sporadic AD patients show predictable patterns of episodic memory loss. MicroRNA (miRNA) deregulation is well established in AD brain but it is unclear whether Aβ or TAU pathology drives thos...

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Detalles Bibliográficos
Autores principales: Sierksma, Annerieke, Lu, Ashley, Salta, Evgenia, Vanden Eynden, Elke, Callaerts-Vegh, Zsuzsanna, D’Hooge, Rudi, Blum, David, Buée, Luc, Fiers, Mark, De Strooper, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186090/
https://www.ncbi.nlm.nih.gov/pubmed/30314521
http://dx.doi.org/10.1186/s13024-018-0285-1