cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction

BACKGROUND: The nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) signaling pathway, plays a critical role in the pathogenesis of pulmonary arterial hypertension (PAH); however, its exact molecular mechanism remains undefined. METHODS: Biotin-cGMP pull-down assay wa...

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Detalles Bibliográficos
Autores principales: Zou, Lihui, Zhang, Junhua, Han, Jingli, Li, Wenqing, Su, Fei, Xu, Xiaomao, Zhai, Zhenguo, Xiao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186101/
https://www.ncbi.nlm.nih.gov/pubmed/30314482
http://dx.doi.org/10.1186/s12931-018-0903-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186101/
https://www.ncbi.nlm.nih.gov/pubmed/30314482
http://dx.doi.org/10.1186/s12931-018-0903-z

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