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Identification of Key Genes and Pathways Associated with RUNX1 Mutations in Acute Myeloid Leukemia Using Bioinformatics Analysis

BACKGROUND: RUNXl plays a key regulatory role in the process of hematopoiesis and is a common target for multiple chromosomal translocations in human acute leukemia. Mutations of RUNX1 gene can lead to acute leukemia and affect the prognosis of AML patients. We aimed to identify pivotal genes and pa...

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Detalles Bibliográficos
Autores principales:	Zhu, Fangxiao, Huang, Rui, Li, Jing, Liao, Xiwen, Huang, Yumei, Lai, Yongrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186152/ https://www.ncbi.nlm.nih.gov/pubmed/30289875 http://dx.doi.org/10.12659/MSM910916

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