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Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children

In this multicenter study, we identified an increased risk of 30-day mortality among hospitalized children with carbapenem-resistant Enterobacteriaceae (CRE) isolated from clinical cultures compared with those with carbapenem-susceptible Enterobacteriaceae. We additionally report significant variati...

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Detalles Bibliográficos
Autores principales: Chiotos, Kathleen, Tamma, Pranita D, Flett, Kelly B, Karandikar, Manjiree V, Nemati, Koorosh, Bilker, Warren B, Zaoutis, Theoklis, Han, Jennifer H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186173/
https://www.ncbi.nlm.nih.gov/pubmed/30338267
http://dx.doi.org/10.1093/ofid/ofy222
Descripción
Sumario:In this multicenter study, we identified an increased risk of 30-day mortality among hospitalized children with carbapenem-resistant Enterobacteriaceae (CRE) isolated from clinical cultures compared with those with carbapenem-susceptible Enterobacteriaceae. We additionally report significant variation in antibiotic treatment for children with CRE infections with infrequent use of combination therapy.