Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children

In this multicenter study, we identified an increased risk of 30-day mortality among hospitalized children with carbapenem-resistant Enterobacteriaceae (CRE) isolated from clinical cultures compared with those with carbapenem-susceptible Enterobacteriaceae. We additionally report significant variati...

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Autores principales: Chiotos, Kathleen, Tamma, Pranita D, Flett, Kelly B, Karandikar, Manjiree V, Nemati, Koorosh, Bilker, Warren B, Zaoutis, Theoklis, Han, Jennifer H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186173/
https://www.ncbi.nlm.nih.gov/pubmed/30338267
http://dx.doi.org/10.1093/ofid/ofy222
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author Chiotos, Kathleen
Tamma, Pranita D
Flett, Kelly B
Karandikar, Manjiree V
Nemati, Koorosh
Bilker, Warren B
Zaoutis, Theoklis
Han, Jennifer H
author_facet Chiotos, Kathleen
Tamma, Pranita D
Flett, Kelly B
Karandikar, Manjiree V
Nemati, Koorosh
Bilker, Warren B
Zaoutis, Theoklis
Han, Jennifer H
author_sort Chiotos, Kathleen
collection PubMed
description In this multicenter study, we identified an increased risk of 30-day mortality among hospitalized children with carbapenem-resistant Enterobacteriaceae (CRE) isolated from clinical cultures compared with those with carbapenem-susceptible Enterobacteriaceae. We additionally report significant variation in antibiotic treatment for children with CRE infections with infrequent use of combination therapy.
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spelling pubmed-61861732018-10-18 Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children Chiotos, Kathleen Tamma, Pranita D Flett, Kelly B Karandikar, Manjiree V Nemati, Koorosh Bilker, Warren B Zaoutis, Theoklis Han, Jennifer H Open Forum Infect Dis Brief Report In this multicenter study, we identified an increased risk of 30-day mortality among hospitalized children with carbapenem-resistant Enterobacteriaceae (CRE) isolated from clinical cultures compared with those with carbapenem-susceptible Enterobacteriaceae. We additionally report significant variation in antibiotic treatment for children with CRE infections with infrequent use of combination therapy. Oxford University Press 2018-09-10 /pmc/articles/PMC6186173/ /pubmed/30338267 http://dx.doi.org/10.1093/ofid/ofy222 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Chiotos, Kathleen
Tamma, Pranita D
Flett, Kelly B
Karandikar, Manjiree V
Nemati, Koorosh
Bilker, Warren B
Zaoutis, Theoklis
Han, Jennifer H
Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children
title Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children
title_full Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children
title_fullStr Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children
title_full_unstemmed Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children
title_short Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children
title_sort increased 30-day mortality associated with carbapenem-resistant enterobacteriaceae in children
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186173/
https://www.ncbi.nlm.nih.gov/pubmed/30338267
http://dx.doi.org/10.1093/ofid/ofy222
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