Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy

Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient pre...

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Autores principales: Agasthi, Pradyumna, Narayanasamy, Hemalatha, Sorajja, Dan, Slack, James, Mookadam, Farouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186336/
https://www.ncbi.nlm.nih.gov/pubmed/30363961
http://dx.doi.org/10.1155/2018/3953579
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author Agasthi, Pradyumna
Narayanasamy, Hemalatha
Sorajja, Dan
Slack, James
Mookadam, Farouk
author_facet Agasthi, Pradyumna
Narayanasamy, Hemalatha
Sorajja, Dan
Slack, James
Mookadam, Farouk
author_sort Agasthi, Pradyumna
collection PubMed
description Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline.
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spelling pubmed-61863362018-10-24 Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy Agasthi, Pradyumna Narayanasamy, Hemalatha Sorajja, Dan Slack, James Mookadam, Farouk Case Rep Cardiol Case Report Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline. Hindawi 2018-09-30 /pmc/articles/PMC6186336/ /pubmed/30363961 http://dx.doi.org/10.1155/2018/3953579 Text en Copyright © 2018 Pradyumna Agasthi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Agasthi, Pradyumna
Narayanasamy, Hemalatha
Sorajja, Dan
Slack, James
Mookadam, Farouk
Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_full Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_fullStr Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_full_unstemmed Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_short Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy
title_sort decitabine induced delayed cardiomyopathy in hematologic malignancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186336/
https://www.ncbi.nlm.nih.gov/pubmed/30363961
http://dx.doi.org/10.1155/2018/3953579
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AT slackjames decitabineinduceddelayedcardiomyopathyinhematologicmalignancy
AT mookadamfarouk decitabineinduceddelayedcardiomyopathyinhematologicmalignancy

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