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The Causal Role of Mitochondrial Dynamics in Regulating Insulin Resistance in Diabetes: Link through Mitochondrial Reactive Oxygen Species
BACKGROUND: Mitochondrial dynamics (mtDYN) has been proposed as a bridge between mitochondrial dysfunction and insulin resistance (IR), which is involved in the pathogenesis of type 2 diabetes (T2D). Our previous study has identified that mitochondrial DNA (mtDNA) haplogroup B4 is a T2D-susceptible...
Autores principales: | Lin, Hung-Yu, Weng, Shao-Wen, Chang, Yen-Hsiang, Su, Yu-Jih, Chang, Chih-Min, Tsai, Chia-Jen, Shen, Feng-Chih, Chuang, Jiin-Haur, Lin, Tsu-Kung, Liou, Chia-Wei, Lin, Ching-Yi, Wang, Pei-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186363/ https://www.ncbi.nlm.nih.gov/pubmed/30363990 http://dx.doi.org/10.1155/2018/7514383 |
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