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AB088. Inhibition of prongf pathway restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse
BACKGROUND: Patients with diabetic erectile dysfunction (ED) usually respond poorly to oral phosphodiesterase-5 inhibitors due to a lack of bioavailable nitric oxide from severe endothelial and neural dysfunction. ProNGF and its receptor p75(NTR) are known to be up-regulated in diabetic condition an...
Autores principales: | Minh, Nguyen Nhat, Song, Kang-Moon, Choi, Min-Ji, Ghatak, Kalyan, Kwon, Mi-Hye, Yin, Guo Nan, Ryu, Ji-Kan, Suh, Jun-Kyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186664/ http://dx.doi.org/10.21037/tau.2018.AB088 |
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