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AB042. Oxidative stress and male infertility

Infertility is a condition associated with major medical and social preoccupation. A male etiology is responsible for nearly half the cases of infertility and is caused by alterations in sperm concentration, motility, and/or morphology. Recent advances in the field of infertility have greatly influe...

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Detalles Bibliográficos
Autor principal: Xing, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186691/
http://dx.doi.org/10.21037/tau.2018.AB042
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author Xing, Junping
author_facet Xing, Junping
author_sort Xing, Junping
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description Infertility is a condition associated with major medical and social preoccupation. A male etiology is responsible for nearly half the cases of infertility and is caused by alterations in sperm concentration, motility, and/or morphology. Recent advances in the field of infertility have greatly influenced our understanding of the different circumstances attributing to male factor infertility. While environmental, physiological, and genetic influences were recognized, at the molecular level, oxidative stress (OS) resulting from the imbalance between oxidants and reductants appears to be a common denominator impairing sperm function and delaying pregnancy. This review discusses the mechanisms by which reactive oxygen species (ROS) develop in semen and their role in the pathophysiology of male infertility.
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spelling pubmed-61866912018-10-26 AB042. Oxidative stress and male infertility Xing, Junping Transl Androl Urol Podium Lecture Infertility is a condition associated with major medical and social preoccupation. A male etiology is responsible for nearly half the cases of infertility and is caused by alterations in sperm concentration, motility, and/or morphology. Recent advances in the field of infertility have greatly influenced our understanding of the different circumstances attributing to male factor infertility. While environmental, physiological, and genetic influences were recognized, at the molecular level, oxidative stress (OS) resulting from the imbalance between oxidants and reductants appears to be a common denominator impairing sperm function and delaying pregnancy. This review discusses the mechanisms by which reactive oxygen species (ROS) develop in semen and their role in the pathophysiology of male infertility. AME Publishing Company 2018-09 /pmc/articles/PMC6186691/ http://dx.doi.org/10.21037/tau.2018.AB042 Text en 2018 Translational Andrology and Urology. All rights reserved.
spellingShingle Podium Lecture
Xing, Junping
AB042. Oxidative stress and male infertility
title AB042. Oxidative stress and male infertility
title_full AB042. Oxidative stress and male infertility
title_fullStr AB042. Oxidative stress and male infertility
title_full_unstemmed AB042. Oxidative stress and male infertility
title_short AB042. Oxidative stress and male infertility
title_sort ab042. oxidative stress and male infertility
topic Podium Lecture
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186691/
http://dx.doi.org/10.21037/tau.2018.AB042
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