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AB042. Oxidative stress and male infertility
Infertility is a condition associated with major medical and social preoccupation. A male etiology is responsible for nearly half the cases of infertility and is caused by alterations in sperm concentration, motility, and/or morphology. Recent advances in the field of infertility have greatly influe...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186691/ http://dx.doi.org/10.21037/tau.2018.AB042 |
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author | Xing, Junping |
author_facet | Xing, Junping |
author_sort | Xing, Junping |
collection | PubMed |
description | Infertility is a condition associated with major medical and social preoccupation. A male etiology is responsible for nearly half the cases of infertility and is caused by alterations in sperm concentration, motility, and/or morphology. Recent advances in the field of infertility have greatly influenced our understanding of the different circumstances attributing to male factor infertility. While environmental, physiological, and genetic influences were recognized, at the molecular level, oxidative stress (OS) resulting from the imbalance between oxidants and reductants appears to be a common denominator impairing sperm function and delaying pregnancy. This review discusses the mechanisms by which reactive oxygen species (ROS) develop in semen and their role in the pathophysiology of male infertility. |
format | Online Article Text |
id | pubmed-6186691 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-61866912018-10-26 AB042. Oxidative stress and male infertility Xing, Junping Transl Androl Urol Podium Lecture Infertility is a condition associated with major medical and social preoccupation. A male etiology is responsible for nearly half the cases of infertility and is caused by alterations in sperm concentration, motility, and/or morphology. Recent advances in the field of infertility have greatly influenced our understanding of the different circumstances attributing to male factor infertility. While environmental, physiological, and genetic influences were recognized, at the molecular level, oxidative stress (OS) resulting from the imbalance between oxidants and reductants appears to be a common denominator impairing sperm function and delaying pregnancy. This review discusses the mechanisms by which reactive oxygen species (ROS) develop in semen and their role in the pathophysiology of male infertility. AME Publishing Company 2018-09 /pmc/articles/PMC6186691/ http://dx.doi.org/10.21037/tau.2018.AB042 Text en 2018 Translational Andrology and Urology. All rights reserved. |
spellingShingle | Podium Lecture Xing, Junping AB042. Oxidative stress and male infertility |
title | AB042. Oxidative stress and male infertility |
title_full | AB042. Oxidative stress and male infertility |
title_fullStr | AB042. Oxidative stress and male infertility |
title_full_unstemmed | AB042. Oxidative stress and male infertility |
title_short | AB042. Oxidative stress and male infertility |
title_sort | ab042. oxidative stress and male infertility |
topic | Podium Lecture |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186691/ http://dx.doi.org/10.21037/tau.2018.AB042 |
work_keys_str_mv | AT xingjunping ab042oxidativestressandmaleinfertility |