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AB066. The diagnostic value of narrow-band imaging for flat bladder lesions

BACKGROUND: To investigate the diagnostic value of narrow-band imaging for flat bladder lesions. METHODS: Forty-nine patients with flat bladder lesions diagnosed by white light cystoscopy + narrow-band imaging followed by transurethral resection were included. The diagnostic value of narrow-band ima...

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Autores principales: Chang, Yifan, Sun, Yinghao, Zhang, Zhensheng, Xu, Weidong, Hua, Meimian, Wang, Maoyu, Wang, Aiguo, Xu, Chuanliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186723/
http://dx.doi.org/10.21037/tau.2018.AB066
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author Chang, Yifan
Sun, Yinghao
Zhang, Zhensheng
Xu, Weidong
Hua, Meimian
Wang, Maoyu
Wang, Aiguo
Xu, Chuanliang
author_facet Chang, Yifan
Sun, Yinghao
Zhang, Zhensheng
Xu, Weidong
Hua, Meimian
Wang, Maoyu
Wang, Aiguo
Xu, Chuanliang
author_sort Chang, Yifan
collection PubMed
description BACKGROUND: To investigate the diagnostic value of narrow-band imaging for flat bladder lesions. METHODS: Forty-nine patients with flat bladder lesions diagnosed by white light cystoscopy + narrow-band imaging followed by transurethral resection were included. The diagnostic value of narrow-band imaging was compared with postoperative pathological results. RESULTS: A total of 59 flat lesions were identified, in which 8 were normal urothelium, 3 were chronic inflammation, 1 was papillary urothelial neoplasm of low malignant potential, 2 were mild dysplasia, 1 was moderate dysplasia, 1 was severe dysplasia, 3 were carcinoma in situ, 16 were low-grade papillary urothelial carcinoma, 16 were high-grade papillary urothelial carcinoma, and 8 were invasive papillary urothelial carcinoma. For narrow-band imaging, the sensitivity was 86.7% (39/45), specificity was 57.1% (8/14), diagnostic accuracy was 79.7% (47/59), false-positive rate was 42.9% (6/14), positive predictive value was 86.7% (39/45), negative predictive value was 57.1% (8/14), area under receiver operating characteristic (ROC) curve was 0.719. Among these lesions, the sensitivity and specificity for postoperative recurrent lesions were 100% (3/3) and 40% (2/5), respectively, and those for erythematous patch-like lesions were 90% (9/10) and 100% (4/4), respectively. CONCLUSIONS: Narrow-band imaging can improve the detection rate for flat bladder tumor lesions, and reduce the risk for missed diagnosis under white light cystoscopy, especially for otherwise indistinguishable erythematous patch-like lesions.
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spelling pubmed-61867232018-10-26 AB066. The diagnostic value of narrow-band imaging for flat bladder lesions Chang, Yifan Sun, Yinghao Zhang, Zhensheng Xu, Weidong Hua, Meimian Wang, Maoyu Wang, Aiguo Xu, Chuanliang Transl Androl Urol Printed Abstract BACKGROUND: To investigate the diagnostic value of narrow-band imaging for flat bladder lesions. METHODS: Forty-nine patients with flat bladder lesions diagnosed by white light cystoscopy + narrow-band imaging followed by transurethral resection were included. The diagnostic value of narrow-band imaging was compared with postoperative pathological results. RESULTS: A total of 59 flat lesions were identified, in which 8 were normal urothelium, 3 were chronic inflammation, 1 was papillary urothelial neoplasm of low malignant potential, 2 were mild dysplasia, 1 was moderate dysplasia, 1 was severe dysplasia, 3 were carcinoma in situ, 16 were low-grade papillary urothelial carcinoma, 16 were high-grade papillary urothelial carcinoma, and 8 were invasive papillary urothelial carcinoma. For narrow-band imaging, the sensitivity was 86.7% (39/45), specificity was 57.1% (8/14), diagnostic accuracy was 79.7% (47/59), false-positive rate was 42.9% (6/14), positive predictive value was 86.7% (39/45), negative predictive value was 57.1% (8/14), area under receiver operating characteristic (ROC) curve was 0.719. Among these lesions, the sensitivity and specificity for postoperative recurrent lesions were 100% (3/3) and 40% (2/5), respectively, and those for erythematous patch-like lesions were 90% (9/10) and 100% (4/4), respectively. CONCLUSIONS: Narrow-band imaging can improve the detection rate for flat bladder tumor lesions, and reduce the risk for missed diagnosis under white light cystoscopy, especially for otherwise indistinguishable erythematous patch-like lesions. AME Publishing Company 2018-09 /pmc/articles/PMC6186723/ http://dx.doi.org/10.21037/tau.2018.AB066 Text en 2018 Translational Andrology and Urology. All rights reserved.
spellingShingle Printed Abstract
Chang, Yifan
Sun, Yinghao
Zhang, Zhensheng
Xu, Weidong
Hua, Meimian
Wang, Maoyu
Wang, Aiguo
Xu, Chuanliang
AB066. The diagnostic value of narrow-band imaging for flat bladder lesions
title AB066. The diagnostic value of narrow-band imaging for flat bladder lesions
title_full AB066. The diagnostic value of narrow-band imaging for flat bladder lesions
title_fullStr AB066. The diagnostic value of narrow-band imaging for flat bladder lesions
title_full_unstemmed AB066. The diagnostic value of narrow-band imaging for flat bladder lesions
title_short AB066. The diagnostic value of narrow-band imaging for flat bladder lesions
title_sort ab066. the diagnostic value of narrow-band imaging for flat bladder lesions
topic Printed Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186723/
http://dx.doi.org/10.21037/tau.2018.AB066
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