Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes

The postnatal mammary gland undergoes repeated cycles of proliferation and cell death, most notably when the fully differentiated (lactating) gland dedifferentiates to a prelactation state. Accumulation of milk proteins in the secretory epithelium creates the stress signal that triggers this process...

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Detalles Bibliográficos
Autores principales: Wärri, Anni, Cook, Katherine L., Hu, Rong, Jin, Lu, Zwart, Alan, Soto-Pantoja, David R., Liu, Jie, Finkel, Toren, Clarke, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186758/
https://www.ncbi.nlm.nih.gov/pubmed/30345078
http://dx.doi.org/10.1038/s41420-018-0105-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186758/
https://www.ncbi.nlm.nih.gov/pubmed/30345078
http://dx.doi.org/10.1038/s41420-018-0105-y

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