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Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium

Like other neurons, retinal cells utilize autophagic pathways to maintain cell homeostasis. The mammalian retina relies on heterophagy and selective autophagy to efficiently degrade and metabolize ingested lipids with disruption in autophagy associated degradation contributing to age related retinal...

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Detalles Bibliográficos
Autores principales: Dhingra, Anuradha, Bell, Brent A., Peachey, Neal S., Daniele, Lauren L., Reyes-Reveles, Juan, Sharp, Rachel C., Jun, Bokkyoo, Bazan, Nicolas G., Sparrow, Janet R., Kim, Hye Jin, Philp, Nancy J., Boesze-Battaglia, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186781/
https://www.ncbi.nlm.nih.gov/pubmed/30349463
http://dx.doi.org/10.3389/fncel.2018.00351