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Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium
Like other neurons, retinal cells utilize autophagic pathways to maintain cell homeostasis. The mammalian retina relies on heterophagy and selective autophagy to efficiently degrade and metabolize ingested lipids with disruption in autophagy associated degradation contributing to age related retinal...
Autores principales: | Dhingra, Anuradha, Bell, Brent A., Peachey, Neal S., Daniele, Lauren L., Reyes-Reveles, Juan, Sharp, Rachel C., Jun, Bokkyoo, Bazan, Nicolas G., Sparrow, Janet R., Kim, Hye Jin, Philp, Nancy J., Boesze-Battaglia, Kathleen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186781/ https://www.ncbi.nlm.nih.gov/pubmed/30349463 http://dx.doi.org/10.3389/fncel.2018.00351 |
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