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Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b
Genome-wide association studies as well as lymphatic expression analyses have linked both Cbl-b and GM-CSF to human multiple sclerosis as well as other autoimmune diseases. Both Cbl-b and GM-CSF have been shown to play a prominent role in the development of murine encephalomyelitis; however, no func...
Autores principales: | Peer, Sebastian, Cappellano, Giuseppe, Hermann-Kleiter, Natascha, Albrecht-Schgoer, Karin, Hinterleitner, Reinhard, Baier, Gottfried, Gruber, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186797/ https://www.ncbi.nlm.nih.gov/pubmed/30349541 http://dx.doi.org/10.3389/fimmu.2018.02311 |
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