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Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis
Myocarditis is an inflammatory disease of the heart muscle most commonly caused by viral infection and often maintained by autoimmunity. Virus-induced tissue damage triggers chemokine production and, subsequently, immune cell infiltration with pro-inflammatory and pro-fibrotic cytokine production fo...
Autores principales: | Meyer, Ingmar Sören, Goetzke, Carl Christoph, Kespohl, Meike, Sauter, Martina, Heuser, Arnd, Eckstein, Volker, Vornlocher, Hans-Peter, Anderson, Daniel G., Haas, Jan, Meder, Benjamin, Katus, Hugo Albert, Klingel, Karin, Beling, Antje, Leuschner, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186826/ https://www.ncbi.nlm.nih.gov/pubmed/30349538 http://dx.doi.org/10.3389/fimmu.2018.02303 |
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