Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis

We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized stud...

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Detalles Bibliográficos
Autores principales: Parks, Tom, Wilson, Clare, Curtis, Nigel, Norrby-Teglund, Anna, Sriskandan, Shiranee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186853/
https://www.ncbi.nlm.nih.gov/pubmed/29788397
http://dx.doi.org/10.1093/cid/ciy401
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author Parks, Tom
Wilson, Clare
Curtis, Nigel
Norrby-Teglund, Anna
Sriskandan, Shiranee
author_facet Parks, Tom
Wilson, Clare
Curtis, Nigel
Norrby-Teglund, Anna
Sriskandan, Shiranee
author_sort Parks, Tom
collection PubMed
description We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies.
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spelling pubmed-61868532018-10-18 Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis Parks, Tom Wilson, Clare Curtis, Nigel Norrby-Teglund, Anna Sriskandan, Shiranee Clin Infect Dis Brief Reports We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies. Oxford University Press 2018-11-01 2018-05-18 /pmc/articles/PMC6186853/ /pubmed/29788397 http://dx.doi.org/10.1093/cid/ciy401 Text en © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Parks, Tom
Wilson, Clare
Curtis, Nigel
Norrby-Teglund, Anna
Sriskandan, Shiranee
Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis
title Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis
title_full Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis
title_fullStr Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis
title_full_unstemmed Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis
title_short Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis
title_sort polyspecific intravenous immunoglobulin in clindamycin-treated patients with streptococcal toxic shock syndrome: a systematic review and meta-analysis
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186853/
https://www.ncbi.nlm.nih.gov/pubmed/29788397
http://dx.doi.org/10.1093/cid/ciy401
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