The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog

Lamotrigine is a sodium and calcium channel blocker, used to treat seizures in people. Dogs metabolize Lamotrigine to a cardiotoxic metabolite that causes severe, often fatal ventricular arrhythmias. This report documents the successful treatment of refractory Lamotrigine cardiotoxicity in a dog, us...

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Detalles Bibliográficos
Autores principales: Bellis, Tara J., Gibeon, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186877/
https://www.ncbi.nlm.nih.gov/pubmed/30349712
http://dx.doi.org/10.1002/ccr3.1733
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author Bellis, Tara J.
Gibeon, Laura
author_facet Bellis, Tara J.
Gibeon, Laura
author_sort Bellis, Tara J.
collection PubMed
description Lamotrigine is a sodium and calcium channel blocker, used to treat seizures in people. Dogs metabolize Lamotrigine to a cardiotoxic metabolite that causes severe, often fatal ventricular arrhythmias. This report documents the successful treatment of refractory Lamotrigine cardiotoxicity in a dog, using intralipid emulsion therapy.
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spelling pubmed-61868772018-10-22 The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog Bellis, Tara J. Gibeon, Laura Clin Case Rep Case Reports Lamotrigine is a sodium and calcium channel blocker, used to treat seizures in people. Dogs metabolize Lamotrigine to a cardiotoxic metabolite that causes severe, often fatal ventricular arrhythmias. This report documents the successful treatment of refractory Lamotrigine cardiotoxicity in a dog, using intralipid emulsion therapy. John Wiley and Sons Inc. 2018-08-30 /pmc/articles/PMC6186877/ /pubmed/30349712 http://dx.doi.org/10.1002/ccr3.1733 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Bellis, Tara J.
Gibeon, Laura
The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog
title The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog
title_full The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog
title_fullStr The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog
title_full_unstemmed The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog
title_short The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog
title_sort use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186877/
https://www.ncbi.nlm.nih.gov/pubmed/30349712
http://dx.doi.org/10.1002/ccr3.1733
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