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Alcohol consumption and probable rapid eye movement sleep behavior disorder

OBJECTIVE: To systematically examine the association between alcohol intake and likelihood of having probable rapid eye movement sleep behavior disorder (pRBD) 6 years later. METHODS: The study included 11,905 participants (mean age: 47.7 years) of the Kailuan Study, free of stroke, cancer, Parkinso...

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Autores principales: Ma, Chaoran, Pavlova, Milena, Li, Junjuan, Liu, Ying, Sun, Yujie, Huang, Zhe, Wu, Shouling, Gao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186943/
https://www.ncbi.nlm.nih.gov/pubmed/30349852
http://dx.doi.org/10.1002/acn3.630
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author Ma, Chaoran
Pavlova, Milena
Li, Junjuan
Liu, Ying
Sun, Yujie
Huang, Zhe
Wu, Shouling
Gao, Xiang
author_facet Ma, Chaoran
Pavlova, Milena
Li, Junjuan
Liu, Ying
Sun, Yujie
Huang, Zhe
Wu, Shouling
Gao, Xiang
author_sort Ma, Chaoran
collection PubMed
description OBJECTIVE: To systematically examine the association between alcohol intake and likelihood of having probable rapid eye movement sleep behavior disorder (pRBD) 6 years later. METHODS: The study included 11,905 participants (mean age: 47.7 years) of the Kailuan Study, free of stroke, cancer, Parkinson disease, dementia, and head injury in 2006. We determined pRBD using a validated RBD questionnaire–Hong Kong in 2012. Amounts and types of alcohol intake were collected with questionnaire. Participants were categorized into: nondrinkers, light (women: 0–0.4 servings/day; men: 0–0.9 servings/day), moderate (women: 0.5–1.0 servings/day; men: 1–2 servings/day), and heavy drinkers(women: >1 serving/day; men: >2 servings/day). To examine the alcohol‐pRBD relationship, we used logistic regression to calculate odds ratios (ORs) and 95% confidence intervals (CIs), adjusting for demographic characteristics, smoking, hypertension, diabetes, physical activity, body mass index, and plasma concentrations of lipids and urate. RESULTS: Compared with nondrinkers, current drinkers had a 23% higher likelihood of having pRBD (adjusted OR 1.23, 95% CI 1.07–1.59). Both moderate (adjusted OR: 1.53, 95% CI 1.01–2.30) and heavy drinkers (adjusted OR: 1.29, 95% CI 1.00–1.66), but not light drinkers (adjusted OR: 1.16, 95% CI 0.94–1.44), had a significantly higher likelihood of having pRBD, relative to nondrinkers. There was a nonsignificant trend between consumption of each individual alcoholic beverages (i.e., beer, wine, or hard liquor) and higher likelihood of having pRBD (adjusted ORs ranged from 1.11 to 1.49). CONCLUSIONS: Alcohol consumption was associated with a higher likelihood of having pRBD. Future prospective studies with clinically confirmed RBD, large sample size for information on types of alcoholic beverage are warranted.
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spelling pubmed-61869432018-10-22 Alcohol consumption and probable rapid eye movement sleep behavior disorder Ma, Chaoran Pavlova, Milena Li, Junjuan Liu, Ying Sun, Yujie Huang, Zhe Wu, Shouling Gao, Xiang Ann Clin Transl Neurol Research Articles OBJECTIVE: To systematically examine the association between alcohol intake and likelihood of having probable rapid eye movement sleep behavior disorder (pRBD) 6 years later. METHODS: The study included 11,905 participants (mean age: 47.7 years) of the Kailuan Study, free of stroke, cancer, Parkinson disease, dementia, and head injury in 2006. We determined pRBD using a validated RBD questionnaire–Hong Kong in 2012. Amounts and types of alcohol intake were collected with questionnaire. Participants were categorized into: nondrinkers, light (women: 0–0.4 servings/day; men: 0–0.9 servings/day), moderate (women: 0.5–1.0 servings/day; men: 1–2 servings/day), and heavy drinkers(women: >1 serving/day; men: >2 servings/day). To examine the alcohol‐pRBD relationship, we used logistic regression to calculate odds ratios (ORs) and 95% confidence intervals (CIs), adjusting for demographic characteristics, smoking, hypertension, diabetes, physical activity, body mass index, and plasma concentrations of lipids and urate. RESULTS: Compared with nondrinkers, current drinkers had a 23% higher likelihood of having pRBD (adjusted OR 1.23, 95% CI 1.07–1.59). Both moderate (adjusted OR: 1.53, 95% CI 1.01–2.30) and heavy drinkers (adjusted OR: 1.29, 95% CI 1.00–1.66), but not light drinkers (adjusted OR: 1.16, 95% CI 0.94–1.44), had a significantly higher likelihood of having pRBD, relative to nondrinkers. There was a nonsignificant trend between consumption of each individual alcoholic beverages (i.e., beer, wine, or hard liquor) and higher likelihood of having pRBD (adjusted ORs ranged from 1.11 to 1.49). CONCLUSIONS: Alcohol consumption was associated with a higher likelihood of having pRBD. Future prospective studies with clinically confirmed RBD, large sample size for information on types of alcoholic beverage are warranted. John Wiley and Sons Inc. 2018-08-18 /pmc/articles/PMC6186943/ /pubmed/30349852 http://dx.doi.org/10.1002/acn3.630 Text en © 2018 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Ma, Chaoran
Pavlova, Milena
Li, Junjuan
Liu, Ying
Sun, Yujie
Huang, Zhe
Wu, Shouling
Gao, Xiang
Alcohol consumption and probable rapid eye movement sleep behavior disorder
title Alcohol consumption and probable rapid eye movement sleep behavior disorder
title_full Alcohol consumption and probable rapid eye movement sleep behavior disorder
title_fullStr Alcohol consumption and probable rapid eye movement sleep behavior disorder
title_full_unstemmed Alcohol consumption and probable rapid eye movement sleep behavior disorder
title_short Alcohol consumption and probable rapid eye movement sleep behavior disorder
title_sort alcohol consumption and probable rapid eye movement sleep behavior disorder
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186943/
https://www.ncbi.nlm.nih.gov/pubmed/30349852
http://dx.doi.org/10.1002/acn3.630
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