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Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma

Introduction: Temozolomide (TMZ) is part of the standard of care for treating glioblastoma multiforme (GBM), an aggressive primary brain tumor. New approaches are needed to enhance therapeutic efficacy and reduce toxicity. GBM tumor cells are dependent on glucose and glutamine while relying heavily...

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Detalles Bibliográficos
Autores principales: Augur, Zachary M., Doyle, Catherine M., Li, Mingyi, Mukherjee, Purna, Seyfried, Thomas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186985/
https://www.ncbi.nlm.nih.gov/pubmed/30349820
http://dx.doi.org/10.3389/fnut.2018.00091