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Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma
Introduction: Temozolomide (TMZ) is part of the standard of care for treating glioblastoma multiforme (GBM), an aggressive primary brain tumor. New approaches are needed to enhance therapeutic efficacy and reduce toxicity. GBM tumor cells are dependent on glucose and glutamine while relying heavily...
Autores principales: | Augur, Zachary M., Doyle, Catherine M., Li, Mingyi, Mukherjee, Purna, Seyfried, Thomas N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186985/ https://www.ncbi.nlm.nih.gov/pubmed/30349820 http://dx.doi.org/10.3389/fnut.2018.00091 |
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