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Droplet Breakup Dynamics in Bi-Layer Bifurcating Microchannel
Breakup of droplets at bi-layer bifurcating junction in polydimethylsiloxane (PDMS) microchannel has been investigated by experiments and numerical simulation. The pressure drop in bi-layer bifurcating channel was investigated and compared with single-layer bifurcating channel. Daughter droplet size...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187458/ https://www.ncbi.nlm.nih.gov/pubmed/30393333 http://dx.doi.org/10.3390/mi9020057 |
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author | Ren, Yong Koh, Kai Seng Yew, Maxine Chin, Jit Kai Chan, Yue Yan, Yuying |
author_facet | Ren, Yong Koh, Kai Seng Yew, Maxine Chin, Jit Kai Chan, Yue Yan, Yuying |
author_sort | Ren, Yong |
collection | PubMed |
description | Breakup of droplets at bi-layer bifurcating junction in polydimethylsiloxane (PDMS) microchannel has been investigated by experiments and numerical simulation. The pressure drop in bi-layer bifurcating channel was investigated and compared with single-layer bifurcating channel. Daughter droplet size variation generated in bi-layer bifurcating microchannel was analyzed. The correlation was proposed to predict the transition between breakup and non-breakup conditions of droplets in bi-layer bifurcating channel using a phase diagram. In the non-breakup regime, droplets exiting port can be switched via tuning flow resistance by controlling radius of curvature, and or channel height ratio. Compared with single-layer bifurcating junction, 3-D cutting in diagonal direction from bi-layer bifurcating junction induces asymmetric fission to form daughter droplets with distinct sizes while each size has good monodispersity. Lower pressure drop is required in the new microsystem. The understanding of the droplet fission in the novel microstructure will enable more versatile control over the emulsion formation, fission and sorting. The model system can be developed to investigate the encapsulation and release kinetics of emulsion templated particles such as drug encapsulated microcapsules as they flow through complex porous media structures, such as blood capillaries or the porous tissue structures, which feature with bifurcating junctions. |
format | Online Article Text |
id | pubmed-6187458 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61874582018-11-01 Droplet Breakup Dynamics in Bi-Layer Bifurcating Microchannel Ren, Yong Koh, Kai Seng Yew, Maxine Chin, Jit Kai Chan, Yue Yan, Yuying Micromachines (Basel) Article Breakup of droplets at bi-layer bifurcating junction in polydimethylsiloxane (PDMS) microchannel has been investigated by experiments and numerical simulation. The pressure drop in bi-layer bifurcating channel was investigated and compared with single-layer bifurcating channel. Daughter droplet size variation generated in bi-layer bifurcating microchannel was analyzed. The correlation was proposed to predict the transition between breakup and non-breakup conditions of droplets in bi-layer bifurcating channel using a phase diagram. In the non-breakup regime, droplets exiting port can be switched via tuning flow resistance by controlling radius of curvature, and or channel height ratio. Compared with single-layer bifurcating junction, 3-D cutting in diagonal direction from bi-layer bifurcating junction induces asymmetric fission to form daughter droplets with distinct sizes while each size has good monodispersity. Lower pressure drop is required in the new microsystem. The understanding of the droplet fission in the novel microstructure will enable more versatile control over the emulsion formation, fission and sorting. The model system can be developed to investigate the encapsulation and release kinetics of emulsion templated particles such as drug encapsulated microcapsules as they flow through complex porous media structures, such as blood capillaries or the porous tissue structures, which feature with bifurcating junctions. MDPI 2018-01-31 /pmc/articles/PMC6187458/ /pubmed/30393333 http://dx.doi.org/10.3390/mi9020057 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ren, Yong Koh, Kai Seng Yew, Maxine Chin, Jit Kai Chan, Yue Yan, Yuying Droplet Breakup Dynamics in Bi-Layer Bifurcating Microchannel |
title | Droplet Breakup Dynamics in Bi-Layer Bifurcating Microchannel |
title_full | Droplet Breakup Dynamics in Bi-Layer Bifurcating Microchannel |
title_fullStr | Droplet Breakup Dynamics in Bi-Layer Bifurcating Microchannel |
title_full_unstemmed | Droplet Breakup Dynamics in Bi-Layer Bifurcating Microchannel |
title_short | Droplet Breakup Dynamics in Bi-Layer Bifurcating Microchannel |
title_sort | droplet breakup dynamics in bi-layer bifurcating microchannel |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187458/ https://www.ncbi.nlm.nih.gov/pubmed/30393333 http://dx.doi.org/10.3390/mi9020057 |
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