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Detection of CRISPR-dCas9 on DNA with Solid-State Nanopores
[Image: see text] Solid-state nanopores have emerged as promising platforms for biosensing including diagnostics for disease detection. Here we show nanopore experiments that detect CRISPR-dCas9, a sequence-specific RNA-guided protein system that specifically binds to a target DNA sequence. While CR...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187524/ https://www.ncbi.nlm.nih.gov/pubmed/30187755 http://dx.doi.org/10.1021/acs.nanolett.8b02968 |