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Theoretical and Experimental Research on Bubble Actuated Micro-Pumps
Bubble actuated micro-pumps have great potential to be integrated into microfluidic systems to allow the independence of peripheral equipment. Previous studies on bubble actuated valveless micro-pumps have been mainly limited to experimental studies and numerical simulations due to the complex behav...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187526/ https://www.ncbi.nlm.nih.gov/pubmed/30424158 http://dx.doi.org/10.3390/mi9050225 |
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author | Qu, Yang Zhou, Junjie Wu, Wei |
author_facet | Qu, Yang Zhou, Junjie Wu, Wei |
author_sort | Qu, Yang |
collection | PubMed |
description | Bubble actuated micro-pumps have great potential to be integrated into microfluidic systems to allow the independence of peripheral equipment. Previous studies on bubble actuated valveless micro-pumps have been mainly limited to experimental studies and numerical simulations due to the complex behavior of bubbles. In this paper, the construction of a mathematical model for a bubble actuated valveless micro-pump considering fluid dynamics, heat and mass transfer and bubble dynamics is described. A prototype was fabricated and tested to verify this theoretical model. The morphological evolution of the driving bubbles during the heating process was observed by a high-speed charge-coupled device (CCD) camera, the flow rate produced by the micro-pump under different working conditions was recorded and the test results were explained by the heat dissipation model. The model in this study was able to precisely predict the flow of micro-pumps in different drive modes. The principle behind defining the heating frequency and the duty cycle based on the pump chamber volume was determined. The study shows the mechanism of bubble controlling and the good prospects of bubble actuated valveless micro-pumps. |
format | Online Article Text |
id | pubmed-6187526 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61875262018-11-01 Theoretical and Experimental Research on Bubble Actuated Micro-Pumps Qu, Yang Zhou, Junjie Wu, Wei Micromachines (Basel) Article Bubble actuated micro-pumps have great potential to be integrated into microfluidic systems to allow the independence of peripheral equipment. Previous studies on bubble actuated valveless micro-pumps have been mainly limited to experimental studies and numerical simulations due to the complex behavior of bubbles. In this paper, the construction of a mathematical model for a bubble actuated valveless micro-pump considering fluid dynamics, heat and mass transfer and bubble dynamics is described. A prototype was fabricated and tested to verify this theoretical model. The morphological evolution of the driving bubbles during the heating process was observed by a high-speed charge-coupled device (CCD) camera, the flow rate produced by the micro-pump under different working conditions was recorded and the test results were explained by the heat dissipation model. The model in this study was able to precisely predict the flow of micro-pumps in different drive modes. The principle behind defining the heating frequency and the duty cycle based on the pump chamber volume was determined. The study shows the mechanism of bubble controlling and the good prospects of bubble actuated valveless micro-pumps. MDPI 2018-05-09 /pmc/articles/PMC6187526/ /pubmed/30424158 http://dx.doi.org/10.3390/mi9050225 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Qu, Yang Zhou, Junjie Wu, Wei Theoretical and Experimental Research on Bubble Actuated Micro-Pumps |
title | Theoretical and Experimental Research on Bubble Actuated Micro-Pumps |
title_full | Theoretical and Experimental Research on Bubble Actuated Micro-Pumps |
title_fullStr | Theoretical and Experimental Research on Bubble Actuated Micro-Pumps |
title_full_unstemmed | Theoretical and Experimental Research on Bubble Actuated Micro-Pumps |
title_short | Theoretical and Experimental Research on Bubble Actuated Micro-Pumps |
title_sort | theoretical and experimental research on bubble actuated micro-pumps |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187526/ https://www.ncbi.nlm.nih.gov/pubmed/30424158 http://dx.doi.org/10.3390/mi9050225 |
work_keys_str_mv | AT quyang theoreticalandexperimentalresearchonbubbleactuatedmicropumps AT zhoujunjie theoreticalandexperimentalresearchonbubbleactuatedmicropumps AT wuwei theoreticalandexperimentalresearchonbubbleactuatedmicropumps |