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Theoretical and Experimental Research on Bubble Actuated Micro-Pumps

Bubble actuated micro-pumps have great potential to be integrated into microfluidic systems to allow the independence of peripheral equipment. Previous studies on bubble actuated valveless micro-pumps have been mainly limited to experimental studies and numerical simulations due to the complex behav...

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Detalles Bibliográficos
Autores principales: Qu, Yang, Zhou, Junjie, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187526/
https://www.ncbi.nlm.nih.gov/pubmed/30424158
http://dx.doi.org/10.3390/mi9050225
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author Qu, Yang
Zhou, Junjie
Wu, Wei
author_facet Qu, Yang
Zhou, Junjie
Wu, Wei
author_sort Qu, Yang
collection PubMed
description Bubble actuated micro-pumps have great potential to be integrated into microfluidic systems to allow the independence of peripheral equipment. Previous studies on bubble actuated valveless micro-pumps have been mainly limited to experimental studies and numerical simulations due to the complex behavior of bubbles. In this paper, the construction of a mathematical model for a bubble actuated valveless micro-pump considering fluid dynamics, heat and mass transfer and bubble dynamics is described. A prototype was fabricated and tested to verify this theoretical model. The morphological evolution of the driving bubbles during the heating process was observed by a high-speed charge-coupled device (CCD) camera, the flow rate produced by the micro-pump under different working conditions was recorded and the test results were explained by the heat dissipation model. The model in this study was able to precisely predict the flow of micro-pumps in different drive modes. The principle behind defining the heating frequency and the duty cycle based on the pump chamber volume was determined. The study shows the mechanism of bubble controlling and the good prospects of bubble actuated valveless micro-pumps.
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spelling pubmed-61875262018-11-01 Theoretical and Experimental Research on Bubble Actuated Micro-Pumps Qu, Yang Zhou, Junjie Wu, Wei Micromachines (Basel) Article Bubble actuated micro-pumps have great potential to be integrated into microfluidic systems to allow the independence of peripheral equipment. Previous studies on bubble actuated valveless micro-pumps have been mainly limited to experimental studies and numerical simulations due to the complex behavior of bubbles. In this paper, the construction of a mathematical model for a bubble actuated valveless micro-pump considering fluid dynamics, heat and mass transfer and bubble dynamics is described. A prototype was fabricated and tested to verify this theoretical model. The morphological evolution of the driving bubbles during the heating process was observed by a high-speed charge-coupled device (CCD) camera, the flow rate produced by the micro-pump under different working conditions was recorded and the test results were explained by the heat dissipation model. The model in this study was able to precisely predict the flow of micro-pumps in different drive modes. The principle behind defining the heating frequency and the duty cycle based on the pump chamber volume was determined. The study shows the mechanism of bubble controlling and the good prospects of bubble actuated valveless micro-pumps. MDPI 2018-05-09 /pmc/articles/PMC6187526/ /pubmed/30424158 http://dx.doi.org/10.3390/mi9050225 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Qu, Yang
Zhou, Junjie
Wu, Wei
Theoretical and Experimental Research on Bubble Actuated Micro-Pumps
title Theoretical and Experimental Research on Bubble Actuated Micro-Pumps
title_full Theoretical and Experimental Research on Bubble Actuated Micro-Pumps
title_fullStr Theoretical and Experimental Research on Bubble Actuated Micro-Pumps
title_full_unstemmed Theoretical and Experimental Research on Bubble Actuated Micro-Pumps
title_short Theoretical and Experimental Research on Bubble Actuated Micro-Pumps
title_sort theoretical and experimental research on bubble actuated micro-pumps
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187526/
https://www.ncbi.nlm.nih.gov/pubmed/30424158
http://dx.doi.org/10.3390/mi9050225
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