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Characterization and Integration of Terahertz Technology within Microfluidic Platforms

In this work, the prospects of integrating terahertz (THz) time-domain spectroscopy (TDS) within polymer-based microfluidic platforms are investigated. The work considers platforms based upon the polar polymers polyethylene terephthalate (PET), polycarbonate (PC), polymethyl-methacrylate (PMMA), pol...

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Autores principales: Alfihed, Salman, Bergen, Mark H., Ciocoiu, Antonia, Holzman, Jonathan F., Foulds, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187527/
https://www.ncbi.nlm.nih.gov/pubmed/30424386
http://dx.doi.org/10.3390/mi9090453
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author Alfihed, Salman
Bergen, Mark H.
Ciocoiu, Antonia
Holzman, Jonathan F.
Foulds, Ian G.
author_facet Alfihed, Salman
Bergen, Mark H.
Ciocoiu, Antonia
Holzman, Jonathan F.
Foulds, Ian G.
author_sort Alfihed, Salman
collection PubMed
description In this work, the prospects of integrating terahertz (THz) time-domain spectroscopy (TDS) within polymer-based microfluidic platforms are investigated. The work considers platforms based upon the polar polymers polyethylene terephthalate (PET), polycarbonate (PC), polymethyl-methacrylate (PMMA), polydimethylsiloxane (PDMS), and the nonpolar polymers fluorinated ethylene propylene (FEP), polystyrene (PS), high-density polyethylene (HDPE), and ultra-high-molecular-weight polyethylene (UHMWPE). The THz absorption coefficients for these polymers are measured. Two microfluidic platforms are then designed, fabricated, and tested, with one being based upon PET, as a representative high-loss polar polymer, and one being based upon UHMWPE, as a representative low-loss nonpolar polymer. It is shown that the UHMWPE microfluidic platform yields reliable measurements of THz absorption coefficients up to a frequency of 1.75 THz, in contrast to the PET microfluidic platform, which functions only up to 1.38 THz. The distinction seen here is attributed to the differing levels of THz absorption and the manifestation of differing f for the systems. Such findings can play an important role in the future integration of THz technology and polymer-based microfluidic systems.
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spelling pubmed-61875272018-11-01 Characterization and Integration of Terahertz Technology within Microfluidic Platforms Alfihed, Salman Bergen, Mark H. Ciocoiu, Antonia Holzman, Jonathan F. Foulds, Ian G. Micromachines (Basel) Article In this work, the prospects of integrating terahertz (THz) time-domain spectroscopy (TDS) within polymer-based microfluidic platforms are investigated. The work considers platforms based upon the polar polymers polyethylene terephthalate (PET), polycarbonate (PC), polymethyl-methacrylate (PMMA), polydimethylsiloxane (PDMS), and the nonpolar polymers fluorinated ethylene propylene (FEP), polystyrene (PS), high-density polyethylene (HDPE), and ultra-high-molecular-weight polyethylene (UHMWPE). The THz absorption coefficients for these polymers are measured. Two microfluidic platforms are then designed, fabricated, and tested, with one being based upon PET, as a representative high-loss polar polymer, and one being based upon UHMWPE, as a representative low-loss nonpolar polymer. It is shown that the UHMWPE microfluidic platform yields reliable measurements of THz absorption coefficients up to a frequency of 1.75 THz, in contrast to the PET microfluidic platform, which functions only up to 1.38 THz. The distinction seen here is attributed to the differing levels of THz absorption and the manifestation of differing f for the systems. Such findings can play an important role in the future integration of THz technology and polymer-based microfluidic systems. MDPI 2018-09-11 /pmc/articles/PMC6187527/ /pubmed/30424386 http://dx.doi.org/10.3390/mi9090453 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alfihed, Salman
Bergen, Mark H.
Ciocoiu, Antonia
Holzman, Jonathan F.
Foulds, Ian G.
Characterization and Integration of Terahertz Technology within Microfluidic Platforms
title Characterization and Integration of Terahertz Technology within Microfluidic Platforms
title_full Characterization and Integration of Terahertz Technology within Microfluidic Platforms
title_fullStr Characterization and Integration of Terahertz Technology within Microfluidic Platforms
title_full_unstemmed Characterization and Integration of Terahertz Technology within Microfluidic Platforms
title_short Characterization and Integration of Terahertz Technology within Microfluidic Platforms
title_sort characterization and integration of terahertz technology within microfluidic platforms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187527/
https://www.ncbi.nlm.nih.gov/pubmed/30424386
http://dx.doi.org/10.3390/mi9090453
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