Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment

This paper presents a simple method of droplet formation using liquids that easily wet polydimethylsiloxane (PDMS) surfaces without any surface treatment. Using only structural features and uniform flow focusing, Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) droplets were formed in the full P...

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Detalles Bibliográficos
Autores principales: Yoon, Dong Hyun, Tanaka, Daiki, Sekiguchi, Tetsushi, Shoji, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187530/
https://www.ncbi.nlm.nih.gov/pubmed/30424401
http://dx.doi.org/10.3390/mi9090468
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author Yoon, Dong Hyun
Tanaka, Daiki
Sekiguchi, Tetsushi
Shoji, Shuichi
author_facet Yoon, Dong Hyun
Tanaka, Daiki
Sekiguchi, Tetsushi
Shoji, Shuichi
author_sort Yoon, Dong Hyun
collection PubMed
description This paper presents a simple method of droplet formation using liquids that easily wet polydimethylsiloxane (PDMS) surfaces without any surface treatment. Using only structural features and uniform flow focusing, Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) droplets were formed in the full PDMS structure. Extrusion channel and three-dimensional flow focusing resulted in effective fluidic conditions for droplet formation and the droplet size could be precisely controlled by controlling the flow rate of each phase. The proposed structure can be utilized as an important element for droplet based research, as well as a droplet generator.
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spelling pubmed-61875302018-11-01 Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment Yoon, Dong Hyun Tanaka, Daiki Sekiguchi, Tetsushi Shoji, Shuichi Micromachines (Basel) Article This paper presents a simple method of droplet formation using liquids that easily wet polydimethylsiloxane (PDMS) surfaces without any surface treatment. Using only structural features and uniform flow focusing, Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) droplets were formed in the full PDMS structure. Extrusion channel and three-dimensional flow focusing resulted in effective fluidic conditions for droplet formation and the droplet size could be precisely controlled by controlling the flow rate of each phase. The proposed structure can be utilized as an important element for droplet based research, as well as a droplet generator. MDPI 2018-09-14 /pmc/articles/PMC6187530/ /pubmed/30424401 http://dx.doi.org/10.3390/mi9090468 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yoon, Dong Hyun
Tanaka, Daiki
Sekiguchi, Tetsushi
Shoji, Shuichi
Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment
title Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment
title_full Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment
title_fullStr Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment
title_full_unstemmed Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment
title_short Structural Formation of Oil-in-Water (O/W) and Water-in-Oil-in-Water (W/O/W) Droplets in PDMS Device Using Protrusion Channel without Hydrophilic Surface Treatment
title_sort structural formation of oil-in-water (o/w) and water-in-oil-in-water (w/o/w) droplets in pdms device using protrusion channel without hydrophilic surface treatment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187530/
https://www.ncbi.nlm.nih.gov/pubmed/30424401
http://dx.doi.org/10.3390/mi9090468
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