Cargando…

The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane

A valveless electromagnetic (EM) micropump with a matrix-patterned magnetic polymer composite actuator membrane structure was successfully designed and fabricated. The composite membrane structure is made of polydemethylsiloxane (PDMS) that is mixed with magnetic particles and patterned in matrix bl...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohd Said, Muzalifah, Yunas, Jumril, Bais, Badariah, Hamzah, Azrul Azlan, Yeop Majlis, Burhanuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187591/
https://www.ncbi.nlm.nih.gov/pubmed/30393292
http://dx.doi.org/10.3390/mi9010013
_version_ 1783363055924543488
author Mohd Said, Muzalifah
Yunas, Jumril
Bais, Badariah
Hamzah, Azrul Azlan
Yeop Majlis, Burhanuddin
author_facet Mohd Said, Muzalifah
Yunas, Jumril
Bais, Badariah
Hamzah, Azrul Azlan
Yeop Majlis, Burhanuddin
author_sort Mohd Said, Muzalifah
collection PubMed
description A valveless electromagnetic (EM) micropump with a matrix-patterned magnetic polymer composite actuator membrane structure was successfully designed and fabricated. The composite membrane structure is made of polydemethylsiloxane (PDMS) that is mixed with magnetic particles and patterned in matrix blocks. The matrix magnetic composite membrane was fabricated using a soft lithography process and expected to have a compact structure having sufficient magnetic force for membrane deformation and maintained membrane flexibility. The magnetic membrane was integrated with the microfluidic system and functionally tested. The experimental results show that a magnetic composite actuator membrane containing of 6% NdFeB is capable of producing a maximum membrane deflection up to 12.87 µm. The functionality test of the EM actuator for fluid pumping resulted in an extremely low sample injection flow rate of approximately 6.523 nL/min. It was also concluded that there is a correlation between the matrix structure of the actuator membrane and the fluid pumping flow rate. The injection flow rate of the EM micropump can be controlled by adjusting the input power supplied to the EM coil, and this is believed to improve the injection accuracy of the drug dosage and have potential in improving the proficiency of the existing drug delivery system.
format Online
Article
Text
id pubmed-6187591
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61875912018-11-01 The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane Mohd Said, Muzalifah Yunas, Jumril Bais, Badariah Hamzah, Azrul Azlan Yeop Majlis, Burhanuddin Micromachines (Basel) Article A valveless electromagnetic (EM) micropump with a matrix-patterned magnetic polymer composite actuator membrane structure was successfully designed and fabricated. The composite membrane structure is made of polydemethylsiloxane (PDMS) that is mixed with magnetic particles and patterned in matrix blocks. The matrix magnetic composite membrane was fabricated using a soft lithography process and expected to have a compact structure having sufficient magnetic force for membrane deformation and maintained membrane flexibility. The magnetic membrane was integrated with the microfluidic system and functionally tested. The experimental results show that a magnetic composite actuator membrane containing of 6% NdFeB is capable of producing a maximum membrane deflection up to 12.87 µm. The functionality test of the EM actuator for fluid pumping resulted in an extremely low sample injection flow rate of approximately 6.523 nL/min. It was also concluded that there is a correlation between the matrix structure of the actuator membrane and the fluid pumping flow rate. The injection flow rate of the EM micropump can be controlled by adjusting the input power supplied to the EM coil, and this is believed to improve the injection accuracy of the drug dosage and have potential in improving the proficiency of the existing drug delivery system. MDPI 2017-12-31 /pmc/articles/PMC6187591/ /pubmed/30393292 http://dx.doi.org/10.3390/mi9010013 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mohd Said, Muzalifah
Yunas, Jumril
Bais, Badariah
Hamzah, Azrul Azlan
Yeop Majlis, Burhanuddin
The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane
title The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane
title_full The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane
title_fullStr The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane
title_full_unstemmed The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane
title_short The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane
title_sort design, fabrication, and testing of an electromagnetic micropump with a matrix-patterned magnetic polymer composite actuator membrane
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187591/
https://www.ncbi.nlm.nih.gov/pubmed/30393292
http://dx.doi.org/10.3390/mi9010013
work_keys_str_mv AT mohdsaidmuzalifah thedesignfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT yunasjumril thedesignfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT baisbadariah thedesignfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT hamzahazrulazlan thedesignfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT yeopmajlisburhanuddin thedesignfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT mohdsaidmuzalifah designfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT yunasjumril designfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT baisbadariah designfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT hamzahazrulazlan designfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane
AT yeopmajlisburhanuddin designfabricationandtestingofanelectromagneticmicropumpwithamatrixpatternedmagneticpolymercompositeactuatormembrane