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Overexpression of quality control proteins reduces prion conversion in prion-infected cells

Prion diseases are fatal infectious neurodegenerative disorders in humans and other animals and are caused by misfolding of the cellular prion protein (PrP(C)) into the pathological isoform PrP(Sc). These diseases have the potential to transmit within or between species, including zoonotic transmiss...

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Detalles Bibliográficos
Autores principales:	Thapa, Simrika, Abdulrahman, Basant, Abdelaziz, Dalia H., Lu, Li, Ben Aissa, Manel, Schatzl, Hermann M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187620/ https://www.ncbi.nlm.nih.gov/pubmed/30154245 http://dx.doi.org/10.1074/jbc.RA118.002754

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