Cargando…

Analytical Model and Experimental Evaluation of the Micro-Scale Thermal Property Sensor for Single-Sided Measurement

We report a new analytical model of the MEMS-based thermal property sensor for samples which are difficult to handle and susceptible to damage by thermal stimulus, such as living cells. Many sensor designs had been reported for thermal property measurements, but only a few of them have considered th...

Descripción completa

Detalles Bibliográficos
Autores principales: Katayama, Takashi, Uesugi, Kaoru, Morishima, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187662/
https://www.ncbi.nlm.nih.gov/pubmed/30424101
http://dx.doi.org/10.3390/mi9040168
_version_ 1783363065774866432
author Katayama, Takashi
Uesugi, Kaoru
Morishima, Keisuke
author_facet Katayama, Takashi
Uesugi, Kaoru
Morishima, Keisuke
author_sort Katayama, Takashi
collection PubMed
description We report a new analytical model of the MEMS-based thermal property sensor for samples which are difficult to handle and susceptible to damage by thermal stimulus, such as living cells. Many sensor designs had been reported for thermal property measurements, but only a few of them have considered the analytical model of the single-sided measurement in which a measurement sample is placed on the sensor substrate. Even in the few designs that have considered the analytical model, their applicable limits are restricted to more than 1 mm length in practical situations. Our new model considers both the sample and the sensor substrate thermal properties and is applicable to a sensor length less than 1 µm. In order to minimize the influence of the heat stimulus to the sample, the model formulates the required heat dissipating time for different sensor geometries. We propose fast and precise detection circuit architecture to realize our model, and we discuss the sensor performance for a number of different designs.
format Online
Article
Text
id pubmed-6187662
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61876622018-11-01 Analytical Model and Experimental Evaluation of the Micro-Scale Thermal Property Sensor for Single-Sided Measurement Katayama, Takashi Uesugi, Kaoru Morishima, Keisuke Micromachines (Basel) Article We report a new analytical model of the MEMS-based thermal property sensor for samples which are difficult to handle and susceptible to damage by thermal stimulus, such as living cells. Many sensor designs had been reported for thermal property measurements, but only a few of them have considered the analytical model of the single-sided measurement in which a measurement sample is placed on the sensor substrate. Even in the few designs that have considered the analytical model, their applicable limits are restricted to more than 1 mm length in practical situations. Our new model considers both the sample and the sensor substrate thermal properties and is applicable to a sensor length less than 1 µm. In order to minimize the influence of the heat stimulus to the sample, the model formulates the required heat dissipating time for different sensor geometries. We propose fast and precise detection circuit architecture to realize our model, and we discuss the sensor performance for a number of different designs. MDPI 2018-04-05 /pmc/articles/PMC6187662/ /pubmed/30424101 http://dx.doi.org/10.3390/mi9040168 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Katayama, Takashi
Uesugi, Kaoru
Morishima, Keisuke
Analytical Model and Experimental Evaluation of the Micro-Scale Thermal Property Sensor for Single-Sided Measurement
title Analytical Model and Experimental Evaluation of the Micro-Scale Thermal Property Sensor for Single-Sided Measurement
title_full Analytical Model and Experimental Evaluation of the Micro-Scale Thermal Property Sensor for Single-Sided Measurement
title_fullStr Analytical Model and Experimental Evaluation of the Micro-Scale Thermal Property Sensor for Single-Sided Measurement
title_full_unstemmed Analytical Model and Experimental Evaluation of the Micro-Scale Thermal Property Sensor for Single-Sided Measurement
title_short Analytical Model and Experimental Evaluation of the Micro-Scale Thermal Property Sensor for Single-Sided Measurement
title_sort analytical model and experimental evaluation of the micro-scale thermal property sensor for single-sided measurement
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187662/
https://www.ncbi.nlm.nih.gov/pubmed/30424101
http://dx.doi.org/10.3390/mi9040168
work_keys_str_mv AT katayamatakashi analyticalmodelandexperimentalevaluationofthemicroscalethermalpropertysensorforsinglesidedmeasurement
AT uesugikaoru analyticalmodelandexperimentalevaluationofthemicroscalethermalpropertysensorforsinglesidedmeasurement
AT morishimakeisuke analyticalmodelandexperimentalevaluationofthemicroscalethermalpropertysensorforsinglesidedmeasurement