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Electroosmotic Flow in Microchannel with Black Silicon Nanostructures
Although electroosmotic flow (EOF) has been applied to drive fluid flow in microfluidic chips, some of the phenomena associated with it can adversely affect the performance of certain applications such as electrophoresis and ion preconcentration. To minimize the undesirable effects, EOF can be suppr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187698/ https://www.ncbi.nlm.nih.gov/pubmed/30424162 http://dx.doi.org/10.3390/mi9050229 |
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author | Lim, An Eng Lim, Chun Yee Lam, Yee Cheong Taboryski, Rafael |
author_facet | Lim, An Eng Lim, Chun Yee Lam, Yee Cheong Taboryski, Rafael |
author_sort | Lim, An Eng |
collection | PubMed |
description | Although electroosmotic flow (EOF) has been applied to drive fluid flow in microfluidic chips, some of the phenomena associated with it can adversely affect the performance of certain applications such as electrophoresis and ion preconcentration. To minimize the undesirable effects, EOF can be suppressed by polymer coatings or introduction of nanostructures. In this work, we presented a novel technique that employs the Dry Etching, Electroplating and Molding (DEEMO) process along with reactive ion etching (RIE), to fabricate microchannel with black silicon nanostructures (prolate hemispheroid-like structures). The effect of black silicon nanostructures on EOF was examined experimentally by current monitoring method, and numerically by finite element simulations. The experimental results showed that the EOF velocity was reduced by 13 ± 7%, which is reasonably close to the simulation results that predict a reduction of approximately 8%. EOF reduction is caused by the distortion of local electric field at the nanostructured surface. Numerical simulations show that the EOF velocity decreases with increasing nanostructure height or decreasing diameter. This reveals the potential of tuning the etching process parameters to generate nanostructures for better EOF suppression. The outcome of this investigation enhances the fundamental understanding of EOF behavior, with implications on the precise EOF control in devices utilizing nanostructured surfaces for chemical and biological analyses. |
format | Online Article Text |
id | pubmed-6187698 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61876982018-11-01 Electroosmotic Flow in Microchannel with Black Silicon Nanostructures Lim, An Eng Lim, Chun Yee Lam, Yee Cheong Taboryski, Rafael Micromachines (Basel) Article Although electroosmotic flow (EOF) has been applied to drive fluid flow in microfluidic chips, some of the phenomena associated with it can adversely affect the performance of certain applications such as electrophoresis and ion preconcentration. To minimize the undesirable effects, EOF can be suppressed by polymer coatings or introduction of nanostructures. In this work, we presented a novel technique that employs the Dry Etching, Electroplating and Molding (DEEMO) process along with reactive ion etching (RIE), to fabricate microchannel with black silicon nanostructures (prolate hemispheroid-like structures). The effect of black silicon nanostructures on EOF was examined experimentally by current monitoring method, and numerically by finite element simulations. The experimental results showed that the EOF velocity was reduced by 13 ± 7%, which is reasonably close to the simulation results that predict a reduction of approximately 8%. EOF reduction is caused by the distortion of local electric field at the nanostructured surface. Numerical simulations show that the EOF velocity decreases with increasing nanostructure height or decreasing diameter. This reveals the potential of tuning the etching process parameters to generate nanostructures for better EOF suppression. The outcome of this investigation enhances the fundamental understanding of EOF behavior, with implications on the precise EOF control in devices utilizing nanostructured surfaces for chemical and biological analyses. MDPI 2018-05-11 /pmc/articles/PMC6187698/ /pubmed/30424162 http://dx.doi.org/10.3390/mi9050229 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lim, An Eng Lim, Chun Yee Lam, Yee Cheong Taboryski, Rafael Electroosmotic Flow in Microchannel with Black Silicon Nanostructures |
title | Electroosmotic Flow in Microchannel with Black Silicon Nanostructures |
title_full | Electroosmotic Flow in Microchannel with Black Silicon Nanostructures |
title_fullStr | Electroosmotic Flow in Microchannel with Black Silicon Nanostructures |
title_full_unstemmed | Electroosmotic Flow in Microchannel with Black Silicon Nanostructures |
title_short | Electroosmotic Flow in Microchannel with Black Silicon Nanostructures |
title_sort | electroosmotic flow in microchannel with black silicon nanostructures |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187698/ https://www.ncbi.nlm.nih.gov/pubmed/30424162 http://dx.doi.org/10.3390/mi9050229 |
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