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Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine
Heterogeneity, frequent diagnostic fluctuation across presentations, and global concerns with the absence of effec-tive treatments all encourage science that moves the field toward individualized or precision medicine in eating disorders. We review recent advances in psychiatric genetics focusing on...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187759/ https://www.ncbi.nlm.nih.gov/pubmed/29473515 http://dx.doi.org/10.2174/1570159X16666180222163450 |
Sumario: | Heterogeneity, frequent diagnostic fluctuation across presentations, and global concerns with the absence of effec-tive treatments all encourage science that moves the field toward individualized or precision medicine in eating disorders. We review recent advances in psychiatric genetics focusing on genome-wide association studies (GWAS) in eating disorders. Given that the only eating disorder to be the subject of GWAS to date is anorexia nervosa, we review anorexia GWAS and enumerate the prospects and challenges of a genomics-driven approach towards personalized intervention in eating disorders. |
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