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Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine

Heterogeneity, frequent diagnostic fluctuation across presentations, and global concerns with the absence of effec-tive treatments all encourage science that moves the field toward individualized or precision medicine in eating disorders. We review recent advances in psychiatric genetics focusing on...

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Detalles Bibliográficos
Autores principales: Breithaupt, Lauren, Hübel, Christopher, Bulik, Cynthia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187759/
https://www.ncbi.nlm.nih.gov/pubmed/29473515
http://dx.doi.org/10.2174/1570159X16666180222163450
Descripción
Sumario:Heterogeneity, frequent diagnostic fluctuation across presentations, and global concerns with the absence of effec-tive treatments all encourage science that moves the field toward individualized or precision medicine in eating disorders. We review recent advances in psychiatric genetics focusing on genome-wide association studies (GWAS) in eating disorders. Given that the only eating disorder to be the subject of GWAS to date is anorexia nervosa, we review anorexia GWAS and enumerate the prospects and challenges of a genomics-driven approach towards personalized intervention in eating disorders.