Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine

Heterogeneity, frequent diagnostic fluctuation across presentations, and global concerns with the absence of effec-tive treatments all encourage science that moves the field toward individualized or precision medicine in eating disorders. We review recent advances in psychiatric genetics focusing on...

Descripción completa

Detalles Bibliográficos
Autores principales: Breithaupt, Lauren, Hübel, Christopher, Bulik, Cynthia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187759/
https://www.ncbi.nlm.nih.gov/pubmed/29473515
http://dx.doi.org/10.2174/1570159X16666180222163450
_version_ 1783363088558325760
author Breithaupt, Lauren
Hübel, Christopher
Bulik, Cynthia M.
author_facet Breithaupt, Lauren
Hübel, Christopher
Bulik, Cynthia M.
author_sort Breithaupt, Lauren
collection PubMed
description Heterogeneity, frequent diagnostic fluctuation across presentations, and global concerns with the absence of effec-tive treatments all encourage science that moves the field toward individualized or precision medicine in eating disorders. We review recent advances in psychiatric genetics focusing on genome-wide association studies (GWAS) in eating disorders. Given that the only eating disorder to be the subject of GWAS to date is anorexia nervosa, we review anorexia GWAS and enumerate the prospects and challenges of a genomics-driven approach towards personalized intervention in eating disorders.
format Online
Article
Text
id pubmed-6187759
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Bentham Science Publishers
record_format MEDLINE/PubMed
spelling pubmed-61877592019-04-01 Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine Breithaupt, Lauren Hübel, Christopher Bulik, Cynthia M. Curr Neuropharmacol Article Heterogeneity, frequent diagnostic fluctuation across presentations, and global concerns with the absence of effec-tive treatments all encourage science that moves the field toward individualized or precision medicine in eating disorders. We review recent advances in psychiatric genetics focusing on genome-wide association studies (GWAS) in eating disorders. Given that the only eating disorder to be the subject of GWAS to date is anorexia nervosa, we review anorexia GWAS and enumerate the prospects and challenges of a genomics-driven approach towards personalized intervention in eating disorders. Bentham Science Publishers 2018-10 2018-10 /pmc/articles/PMC6187759/ /pubmed/29473515 http://dx.doi.org/10.2174/1570159X16666180222163450 Text en © 2018 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Breithaupt, Lauren
Hübel, Christopher
Bulik, Cynthia M.
Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine
title Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine
title_full Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine
title_fullStr Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine
title_full_unstemmed Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine
title_short Updates on Genome-wide Association Findings in Eating Disorders and Future Application to Precision Medicine
title_sort updates on genome-wide association findings in eating disorders and future application to precision medicine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187759/
https://www.ncbi.nlm.nih.gov/pubmed/29473515
http://dx.doi.org/10.2174/1570159X16666180222163450
work_keys_str_mv AT breithauptlauren updatesongenomewideassociationfindingsineatingdisordersandfutureapplicationtoprecisionmedicine
AT hubelchristopher updatesongenomewideassociationfindingsineatingdisordersandfutureapplicationtoprecisionmedicine
AT bulikcynthiam updatesongenomewideassociationfindingsineatingdisordersandfutureapplicationtoprecisionmedicine

Ejemplares similares