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Comparison of the Genetic Alterations between Primary Colorectal Cancers and Their Corresponding Patient-Derived Xenograft Tissues

Patient-derived xenograft (PDX) models are useful tools for tumor biology research and testing the efficacy of candidate anticancer drugs targeting the druggable mutations identified in tumor tissue. However, it is still unknown how much of the genetic alterations identified in primary tumors are co...

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Detalles Bibliográficos
Autores principales: Yu, Sang Mi, Jung, Seung-Hyun, Chung, Yeun-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187809/
https://www.ncbi.nlm.nih.gov/pubmed/30304923
http://dx.doi.org/10.5808/GI.2018.16.2.30