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Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices

Highly fluorinated perfluoropolyether (PFPE) methacrylates are of great interest for transparent and chemically resistant microfluidic chips. However, so far only a few examples of material formulations for three-dimensional (3D) printing of these polymers have been demonstrated. In this paper we sh...

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Detalles Bibliográficos
Autores principales: Kotz, Frederik, Risch, Patrick, Helmer, Dorothea, Rapp, Bastian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187856/
https://www.ncbi.nlm.nih.gov/pubmed/30424049
http://dx.doi.org/10.3390/mi9030115
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author Kotz, Frederik
Risch, Patrick
Helmer, Dorothea
Rapp, Bastian E.
author_facet Kotz, Frederik
Risch, Patrick
Helmer, Dorothea
Rapp, Bastian E.
author_sort Kotz, Frederik
collection PubMed
description Highly fluorinated perfluoropolyether (PFPE) methacrylates are of great interest for transparent and chemically resistant microfluidic chips. However, so far only a few examples of material formulations for three-dimensional (3D) printing of these polymers have been demonstrated. In this paper we show that microfluidic chips can be printed using these highly fluorinated polymers by 3D stereolithography printing. We developed photocurable resin formulations that can be printed in commercial benchtop stereolithography printers. We demonstrate that the developed formulations can be printed with minimal cross-sectional area of 600 µm for monolithic embedded microfluidic channels and 200 µm for open structures. The printed and polymerized PFPE methacrylates show a good transmittance above 70% at wavelengths between 520–900 nm and a high chemical resistance when being exposed to organic solvents. Microfluidic mixers were printed to demonstrate the great variability of different designs that can be printed using stereolithography.
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spelling pubmed-61878562018-11-01 Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices Kotz, Frederik Risch, Patrick Helmer, Dorothea Rapp, Bastian E. Micromachines (Basel) Article Highly fluorinated perfluoropolyether (PFPE) methacrylates are of great interest for transparent and chemically resistant microfluidic chips. However, so far only a few examples of material formulations for three-dimensional (3D) printing of these polymers have been demonstrated. In this paper we show that microfluidic chips can be printed using these highly fluorinated polymers by 3D stereolithography printing. We developed photocurable resin formulations that can be printed in commercial benchtop stereolithography printers. We demonstrate that the developed formulations can be printed with minimal cross-sectional area of 600 µm for monolithic embedded microfluidic channels and 200 µm for open structures. The printed and polymerized PFPE methacrylates show a good transmittance above 70% at wavelengths between 520–900 nm and a high chemical resistance when being exposed to organic solvents. Microfluidic mixers were printed to demonstrate the great variability of different designs that can be printed using stereolithography. MDPI 2018-03-08 /pmc/articles/PMC6187856/ /pubmed/30424049 http://dx.doi.org/10.3390/mi9030115 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kotz, Frederik
Risch, Patrick
Helmer, Dorothea
Rapp, Bastian E.
Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices
title Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices
title_full Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices
title_fullStr Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices
title_full_unstemmed Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices
title_short Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices
title_sort highly fluorinated methacrylates for optical 3d printing of microfluidic devices
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187856/
https://www.ncbi.nlm.nih.gov/pubmed/30424049
http://dx.doi.org/10.3390/mi9030115
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