Cargando…

Inhibitory effects of pentoxifylline on inflammation-related tumorigenesis in rat colon

Chronic inflammation in the colorectum increases the risk of colorectal cancer development. Pentoxifylline, a medicine used for improving the circulation, has been reported to inhibit TNF-α production and to ameliorate inflammatory bowel disease and non-alcoholic steatohepatitis. In this study, we i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shirakami, Yohei, Kochi, Takahiro, Kubota, Masaya, Sakai, Hiroyasu, Ibuka, Takashi, Yoshimi, Kazuto, Kuramoto, Takashi, Tanaka, Takuji, Shimizu, Masahito, Seishima, Mitsuru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188053/ https://www.ncbi.nlm.nih.gov/pubmed/30338039 http://dx.doi.org/10.18632/oncotarget.26119

Ejemplares similares

Inhibitory effects of a selective prostaglandin E2 receptor antagonist RQ-15986 on inflammation-related colon tumorigenesis in APC-mutant rats
por: Shirakami, Yohei, et al.
Publicado: (2021)

Preventive Effects of Pentoxifylline on the Development of Colonic Premalignant Lesions in Obese and Diabetic Mice
por: Fukuta, Kazufumi, et al.
Publicado: (2017)

Preventive effects of the sodium glucose cotransporter 2 inhibitor tofogliflozin on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic mice
por: Obara, Koki, et al.
Publicado: (2017)

Alpha-Glucosidase Inhibitor Voglibose Suppresses Azoxymethane-Induced Colonic Preneoplastic Lesions in Diabetic and Obese Mice
por: Kato, Junichi, et al.
Publicado: (2020)

Inhibitory effects of astaxanthin on azoxymethane-induced colonic preneoplastic lesions in C57/BL/KsJ-db/db mice
por: Kochi, Takahiro, et al.
Publicado: (2014)

Apc-Mutant Kyoto Apc Delta (KAD) Rats Are Susceptible to 4-NQO-Induced Tongue Carcinogenesis
por: Tanaka, Takuji, et al.
Publicado: (2014)

Sodium alginate prevents progression of non-alcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice
por: Miyazaki, Tsuneyuki, et al.
Publicado: (2016)

Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage
por: Ideta, Takayasu, et al.
Publicado: (2017)

Metformin Suppresses Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-+Lepr(db)/+Lepr(db) Mice
por: Ohno, Tomohiko, et al.
Publicado: (2015)

Chemopreventive Potential of Green Tea Catechins in Hepatocellular Carcinoma
por: Shimizu, Masahito, et al.
Publicado: (2015)

Prevention of Colorectal Cancer by Targeting Obesity-Related Disorders and Inflammation
por: Shirakami, Yohei, et al.
Publicado: (2017)

Effects of Indoleamine 2,3-Dioxygenase Deficiency on High-Fat Diet-Induced Hepatic Inflammation
por: Nagano, Junji, et al.
Publicado: (2013)

Enhanced Development of Azoxymethane-Induced Colonic Preneoplastic Lesions in Hypertensive Rats
por: Kochi, Takahiro, et al.
Publicado: (2013)

Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis
por: Miyazaki, Tsuneyuki, et al.
Publicado: (2021)

Preventive effects of the angiotensin-converting enzyme inhibitor, captopril, on the development of azoxymethane-induced colonic preneoplastic lesions in diabetic and hypertensive rats
por: KOCHI, TAKAHIRO, et al.
Publicado: (2014)

The Dipeptidyl Peptidase-4 Inhibitor Teneligliptin Attenuates Hepatic Lipogenesis via AMPK Activation in Non-Alcoholic Fatty Liver Disease Model Mice
por: Ideta, Takayasu, et al.
Publicado: (2015)

(-)-Epigallocatechin-3-gallate suppresses hepatic preneoplastic lesions developed in a novel rat model of non-alcoholic steatohepatitis
por: Sumi, Takafumi, et al.
Publicado: (2013)

Idiopathic Ileocolonic Varices Coexisting with a Colon Polyp Treated Successfully by Endoscopy: A Case Report and Literature Review
por: Miwa, Takao, et al.
Publicado: (2019)

A Novel Mouse Model of Intrahepatic Cholangiocarcinoma Induced by Azoxymethane
por: Shirakami, Yohei, et al.
Publicado: (2023)

The phosphorylated retinoid X receptor-α promotes diethylnitrosamine-induced hepatocarcinogenesis in mice through the activation of β-catenin signaling pathway
por: Sakai, Hiroyasu, et al.
Publicado: (2021)

Synergistic growth inhibition by acyclic retinoid and phosphatidylinositol 3-kinase inhibitor in human hepatoma cells
por: Baba, Atsushi, et al.
Publicado: (2013)

Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice
por: Tanaka, Takuji, et al.
Publicado: (2016)

Erratum: Tanaka, T. et al. Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice. Cancers, 2016, 8, 25
por: Tanaka, Takuji, et al.
Publicado: (2017)

Endoscopic fenestration for benign complete anastomotic obstruction following rectal surgery
por: Takada, Jun, et al.
Publicado: (2022)

Usefulness of water pressure observation in detection and direct clipping of source of colonic diverticular bleeding
por: Takada, Jun, et al.
Publicado: (2023)

A novel aromatic mutagen, 5-amino-6-hydroxy-8H-benzo[6,7]azepino[5,4,3-de]quinolin-7-one (ABAQ), induces colonic preneoplastic lesions in mice
por: Kochi, Takahiro, et al.
Publicado: (2014)

Pitavastatin suppresses diethylnitrosamine-induced liver preneoplasms in male C57BL/KsJ-db/db obese mice
por: Shimizu, Masahito, et al.
Publicado: (2011)

Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay
por: Yoshimi, Kazuto, et al.
Publicado: (2012)

Possible Mechanisms of Green Tea and Its Constituents against Cancer
por: Shirakami, Yohei, et al.
Publicado: (2018)

Micro-RNA Analysis of Pancreatic Cyst Fluid for Diagnosing Malignant Transformation of Intraductal Papillary Mucinous Neoplasm by Comparing Intraductal Papillary Mucinous Adenoma and Carcinoma
por: Shirakami, Yohei, et al.
Publicado: (2021)

Targeting Receptor Tyrosine Kinases for Chemoprevention by Green Tea Catechin, EGCG
por: Shimizu, Masahito, et al.
Publicado: (2008)

Short- and long-term outcomes after colonic self-expandable metal stent placement for malignant large-bowel obstruction as a bridge to surgery focus on the feasibility of the laparoscopic approach: a retrospective, single center study
por: Tajima, Jesse Yu, et al.
Publicado: (2020)

Regulation of the Induction and Function of Cytotoxic T Lymphocytes by Natural Killer T Cell
por: Ito, Hiroyasu, et al.
Publicado: (2010)

Risk factors for pyrexia after endoscopic submucosal dissection of gastric lesions
por: Nakanishi, Takayuki, et al.
Publicado: (2014)

The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis
por: Shibata, Yuhei, et al.
Publicado: (2016)

Symptomatic Acute Pancreatitis Induced by Nilotinib: A Report of Two Cases
por: Yamada, Toshiki, et al.
Publicado: (2016)

Nutraceutical Approach for Preventing Obesity-Related Colorectal and Liver Carcinogenesis
por: Shimizu, Masahito, et al.
Publicado: (2012)

Inhibition of iNOS activity enhances the anti-tumor effects of alpha-galactosylceramide in established murine cancer model
por: Ito, Hiroyasu, et al.
Publicado: (2015)

PHF24 is expressed in the inhibitory interneurons in rats
por: Numakura, Yuki, et al.
Publicado: (2020)

Mac-2-binding protein glycosylation isomer is useful to predict muscle cramps in patients with chronic liver disease
por: Miwa, Takao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f9fg0d2qjgh9ihk7u8q6rns1g0