Cargando…

Estrogen receptor-beta is a potential target for triple negative breast cancer treatment

Triple Negative breast cancer (TNBC) is a subtype of breast cancer that lacks the expression of estrogen receptor (ER), progesterone receptor, and human epidermal growth factor receptor 2. TNBC accounts for 15-20% of all breast cancer cases but accounts for over 50% of mortality. We propose that Est...

Descripción completa

Detalles Bibliográficos
Autores principales:	Austin, David, Hamilton, Nalo, Elshimali, Yahya, Pietras, Richard, Wu, Yanyuan, Vadgama, Jaydutt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188058/ https://www.ncbi.nlm.nih.gov/pubmed/30338035 http://dx.doi.org/10.18632/oncotarget.26089

Ejemplares similares

Biologic Roles of Estrogen Receptor-β and Insulin-Like Growth Factor-2 in Triple-Negative Breast Cancer
por: Hamilton, Nalo, et al.
Publicado: (2015)

Receptors for Insulin-Like Growth Factor-2 and Androgens as Therapeutic Targets in Triple-Negative Breast Cancer
por: Hamilton, Nalo, et al.
Publicado: (2017)

Triple Negative Breast Tumors in African-American and Hispanic/Latina Women Are High in CD44+, Low in CD24+, and Have Loss of PTEN
por: Wu, Yanyuan, et al.
Publicado: (2013)

GROα overexpression drives cell migration and invasion in triple negative breast cancer cells
por: Bhat, Kruttika, et al.
Publicado: (2017)

The Clinical Utilization of Circulating Cell Free DNA (CCFDNA) in Blood of Cancer Patients
por: Elshimali, Yahya I., et al.
Publicado: (2013)

MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis
por: Dutta, Pranabananda, et al.
Publicado: (2018)

Activation of Akt1 accelerates carcinogen-induced tumorigenesis in mammary gland of virgin and post-lactating transgenic mice
por: Wu, Yanyuan, et al.
Publicado: (2014)

AMP-activated protein kinase: a potential therapeutic target for triple-negative breast cancer
por: Cao, Wei, et al.
Publicado: (2019)

Optimization Of Cancer Treatment Through Overcoming Drug Resistance
por: Elshimali, Yahya I., et al.
Publicado: (2018)

From Interaction to Intervention: How Mesenchymal Stem Cells Affect and Target Triple-Negative Breast Cancer
por: Wu, Yong, et al.
Publicado: (2023)

Epithelial-Mesenchymal Transition and Breast Cancer
por: Wu, Yanyuan, et al.
Publicado: (2016)

PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers
por: Keung, Man Yee T., et al.
Publicado: (2019)

Lactate, a Neglected Factor for Diabetes and Cancer Interaction
por: Wu, Yong, et al.
Publicado: (2016)

Genetic variants in African-American and Hispanic patients with breast cancer
por: Dutta, Pranabananda, et al.
Publicado: (2022)

STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits
por: CHUNG, SEYUNG S., et al.
Publicado: (2013)

Response of Breast Cancer Cells to PARP Inhibitors Is Independent of BRCA Status
por: Keung, Man Yee, et al.
Publicado: (2020)

Slug contributes to cancer progression by direct regulation of ERα signaling pathway
por: LI, YOUQIANG, et al.
Publicado: (2015)

ZBED2 expression enhances interferon signaling and predicts better survival of estrogen receptor‐negative breast cancer patients
por: Liu, Dingxie, et al.
Publicado: (2022)

Estrogen receptor beta expression in triple negative breast cancers is not associated with recurrence or survival
por: Takano, Elena A., et al.
Publicado: (2023)

Expression of MALAT1 Promotes Trastuzumab Resistance in HER2 Overexpressing Breast Cancers
por: Wu, Yanyuan, et al.
Publicado: (2020)

Transcriptional Regulation of CCL2 by PARP1 Is a Driver for Invasiveness in Breast Cancer
por: Dutta, Pranabananda, et al.
Publicado: (2020)

Green tea and quercetin sensitize PC-3 xenograft prostate tumors to docetaxel chemotherapy
por: Wang, Piwen, et al.
Publicado: (2016)

Association of Vitamin D3 Level with Breast Cancer Risk and Prognosis in African-American and Hispanic Women
por: Wu, Yanyuan, et al.
Publicado: (2017)

Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
por: Wu, Yanyuan, et al.
Publicado: (2010)

Transcriptomic and ChIP-sequence interrogation of EGFR signaling in HER2+ breast cancer cells reveals a dynamic chromatin landscape and S100 genes as targets
por: Nava, Miguel, et al.
Publicado: (2019)

A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells
por: Wu, Yanyuan, et al.
Publicado: (2017)

Elevated Baseline Serum PD-L1 Level May Predict Poor Outcomes from Breast Cancer in African-American and Hispanic Women
por: Wu, Yanyuan, et al.
Publicado: (2022)

Phytochemicals in Inhibition of Prostate Cancer: Evidence from Molecular Mechanisms Studies
por: Hao, Qiongyu, et al.
Publicado: (2022)

Potential Therapies Targeting the Metabolic Reprogramming of Diabetes-Associated Breast Cancer
por: Shum, Hang Chee Erin, et al.
Publicado: (2023)

IGF-1 Regulates Cyr61 Induced Breast Cancer Cell Proliferation and Invasion
por: Sarkissyan, Suren, et al.
Publicado: (2014)

Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array
por: Chung, Seyung, et al.
Publicado: (2015)

Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancer
por: Wu, Yanyuan, et al.
Publicado: (2008)

Tumor-Derived Exosomes in Tumor-Induced Immune Suppression
por: Hao, Qiongyu, et al.
Publicado: (2022)

Estrogen Receptor Mediates the Radiosensitivity of Triple-Negative Breast Cancer Cells
por: Chen, Xingxing, et al.
Publicado: (2017)

Insights into the Role of Estrogen Receptor β in Triple-Negative Breast Cancer
por: Sellitto, Assunta, et al.
Publicado: (2020)

SUN-LB135 Estrogen Receptor Beta Inhibits NFkB Signaling to Inhibit Triple Negative Breast Cancer
por: Aspros, Kirsten, et al.
Publicado: (2020)

Estrogen Actions in Triple-Negative Breast Cancer
por: Treeck, Oliver, et al.
Publicado: (2020)

Utilization of NGS technologies to investigate transcriptomic and epigenomic mechanisms in trastuzumab resistance
por: Nava, Miguel, et al.
Publicado: (2019)

Vitamin D Receptor Gene Polymorphisms and Prognosis of Breast Cancer among African-American and Hispanic Women
por: Mishra, Dhruva K., et al.
Publicado: (2013)

Roles of Protein Disulfide Isomerase in Breast Cancer
por: Yang, Suhui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hl089t3ekmiguk5s2nni3f3v93