The role of AP-1 in self-sufficient proliferation and migration of cancer cells and its potential impact on an autocrine/paracrine loop

Activating protein-1 (AP-1) family members, especially Fra-1 and c-Jun, are highly expressed in invasive cancers and can mediate enhanced migration and proliferation. The aim of this study was to explore the significance of elevated levels of AP-1 family members under conditions that restrict growth...

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Detalles Bibliográficos
Autores principales: Ibrahim, Sherif Abd El-Fattah, Abudu, Aierken, Jonhson, Eugenia, Aftab, Neelum, Conrad, Susan, Fluck, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188139/
https://www.ncbi.nlm.nih.gov/pubmed/30344941
http://dx.doi.org/10.18632/oncotarget.26047

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