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A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells

The protein crosslinking enzyme tissue transglutaminase (tTG) is an acyltransferase which catalyzes transamidation reactions between two proteins, or between a protein and a polyamine. It is frequently overexpressed in several different types of human cancer cells, where it has been shown to contrib...

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Detalles Bibliográficos
Autores principales: Katt, William P., Blobel, Nicolas J., Komarova, Svetlana, Antonyak, Marc A., Nakano, Ichiro, Cerione, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188150/
https://www.ncbi.nlm.nih.gov/pubmed/30344949
http://dx.doi.org/10.18632/oncotarget.26193